Evidence of a posterior cingulate involvement (Brodmann area 31) in dyslexia: a study based on source localization algorithm of event-related potentials

Progress in Neuro-psychopharmacology & Biological Psychiatry
John StoitsisDimitris Anagnostopoulos

Abstract

The study investigates the differences regarding the position of intracranial generators of P50 component of ERPs in 38 dyslexic children aged 11.47+/-2.12 years compared with their 19 healthy siblings aged 12.21+/-2.25. The dipoles were extracted by solving the inverse electromagnetic problem according to the recursively applied and projected multiple signal classification (RAP-MUSIC) algorithm approach. For improved localization of the main dipole the solutions were optimized using genetic algorithms. The statistical analysis revealed differences regarding the position of intracranial generators of low frequency of P50. Particularly, dyslexics showed main activity being located at posterior cingulate cortex (Brodmann's area 31) while controls exhibited main activity being located at retrosplenial cortex (Brodmann's area 30). These results may indicate a role for the posterior cingulate cortex in the pre-attentive processing operation of dyslexia beyond of its traditional function in terms of spatial attention and motor intention.

References

Jun 1, 1992·IEEE Transactions on Bio-medical Engineering·J C MosherR M Leahy
Jan 1, 1994·Electroencephalography and Clinical Neurophysiology·P Berg, M Scherg
Feb 1, 1996·Journal of Neuroscience Methods·D McNayW W Sutherling
Aug 22, 1996·Proceedings. Biological Sciences·K I McAnally, J F Stein
Mar 24, 1997·Psychiatry Research·G ZouridakisB H Jansen
Sep 15, 1998·IEEE Transactions on Medical Imaging·D L CollinsA C Evans
Sep 19, 1998·Electroencephalography and Clinical Neurophysiology·A Gevins
Jul 7, 2000·Neuroreport·M L SutterK N O'Connor
Apr 27, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Katsuhiro KobayashiJean Gotman
Dec 5, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alberto J R LealJoão P Silva Cunha
Feb 27, 2003·Proceedings of the National Academy of Sciences of the United States of America·Elise TempleJohn D E Gabrieli
May 14, 2003·Journal of Communication Disorders·James W Montgomery
Sep 10, 2003·Journal of Child Psychology and Psychiatry, and Allied Disciplines·M E ToplakR Tannock
Sep 1, 1955·Journal of Abnormal Psychology·J E DOPPELT, W L WALLACE
Nov 11, 2003·Brain and Cognition·Serge RuffJean-François Démonet
Nov 19, 2003·Neural Networks : the Official Journal of the International Neural Network Society·Jörn AnemüllerScott Makeig
Feb 13, 2004·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Frank R VellutinoDonna M Scanlon
Mar 10, 2004·Behavioral and Cognitive Neuroscience Reviews·R Holly Fitch, Paula Tallal
Aug 24, 2004·Current Opinion in Neurobiology·Israel Nelken
Sep 8, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Christoph M MichelRolando Grave de Peralta
Nov 6, 2004·Journal of Child Neurology·Richard I Webster, Michael I Shevell
Nov 13, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Benjamin J Shannon, Randy L Buckner
Jun 14, 2005·Biological Psychiatry·Sally E Shaywitz, Bennett A Shaywitz
Jul 5, 2005·Brain Research. Cognitive Brain Research·Christopher I PetkovMitchell L Sutter
Oct 21, 2005·Neuroreport·Charalabos PapageorgiouConstantin Soldatos

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