Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis

Phytotherapy Research : PTR
Melainie CameronSigrun Chrubasik

Abstract

Herbal medicinal products (HMPs) that interact with the mediators of inflammation are used in the treatment of rheumatoid arthritis (RA). The aim of this study was to update a previous systematic review published in 2000. We searched electronic databases (MEDLINE, EMBASE, CISCOM, AMED, CINAHL, Cochrane registers) to June 2007, unrestricted by date or language, and included randomized controlled trials that compared HMPs with inert (placebo) or active controls in patients with rheumatoid arthritis. Five reviewers contributed to data extraction. Disagreements were discussed and resolved by consensus with reference to Cochrane guidelines and advice from the Cochrane Collaboration. Twenty studies (10 identified for this review update, and 10 of the 11 studies of the original review) investigating 14 HMPs were included. Meta-analysis was restricted to data from previous seven studies with oils from borage, blackcurrant and evening primrose containing gamma linolenic acid (GLA). GLA doses equal or higher than 1400 mg/day showed benefit in the alleviation of rheumatic complaints whereas lower doses ( approximately 500 mg) were ineffective. Three studies compared products from Tripterygium wilfordii (thunder god vine) to placebos and r...Continue Reading

References

Jul 15, 1990·Biochemical Pharmacology·U R KuppusamyN P Das
Feb 1, 1989·Annals of the Rheumatic Diseases·J JänttiH Isomäki
Jul 1, 1989·Annals of the Rheumatic Diseases·M PattrickM Doherty
Jun 1, 1989·Clinical Rheumatology·J JänttiH Isomäki
Oct 1, 1988·The Journal of Pharmacy and Pharmacology·W J Pugh, K Sambo
Jun 1, 1987·Arthritis and Rheumatism·M E PearsonJ C Steigerwald
Oct 25, 1980·Lancet·H O CollierS A Saeed
Feb 1, 1983·Pain·M Fitzgerald
Aug 1, 1994·British Journal of Rheumatology·S H ChanM L Boey
Sep 1, 1994·British Journal of Rheumatology·L J LeventhalR B Zurier
Mar 12, 1994·BMJ : British Medical Journal·D A Atherton
Nov 1, 1993·Annals of Internal Medicine·L J LeventhalR B Zurier
Jan 1, 1993·Journal of Ethnopharmacology·R RizziL A Stivala
Mar 1, 1993·Journal of Ethnopharmacology·H P AmmonJ Sabieraj
May 1, 1996·The British Journal of Surgery·W G JiangM B Hallett
Aug 28, 1996·JAMA : the Journal of the American Medical Association·C BeggD F Stroup
Aug 1, 1997·Chemico-biological Interactions·N Volpi
Aug 1, 1997·Journal of Ethnopharmacology·A Santa MariaJ M Pozuelo
May 30, 1998·JAMA : the Journal of the American Medical Association·J A Astin
Aug 1, 1998·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·U RohnertE F Elstner
Aug 1, 1998·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·U RohnertE F Elstner
Dec 10, 1999·Journal of Agricultural and Food Chemistry·M P KähkönenM Heinonen

❮ Previous
Next ❯

Citations

Jul 23, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Wan-Ru DuanYi-Kuan Xie
Jan 12, 2011·Rheumatic Diseases Clinics of North America·Edzard Ernst
Mar 28, 2017·Nutrients·Mirjana VeselinovicVladimir Jakovljevic
Jan 6, 2018·International Journal of Molecular Sciences·Paweł SulimaJerzy A Przyborowski
Nov 23, 2011·Forschende Komplementärmedizin = Research in Complementary Medicine·Bernhard UehlekeJörg Melzer
Sep 1, 2017·Knee Surgery & Related Research·Joong Il KimMyung Chul Lee
Jan 13, 2011·Phytotherapy Research : PTR·J VlachojannisS Chrubasik
Feb 18, 2011·The Cochrane Database of Systematic Reviews·Melainie CameronSigrun Chrubasik
May 19, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Xuan XiaQingchun Huang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.