Evidence of Improvement in Various Impairments by Exercise Interventions in Patients with Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Clinical Trials

Journal of the Japanese Physical Therapy Association = Rigaku Ryōhō
Ryo TanakaHideki Moriyama

Abstract

To investigate improvement in various impairments by exercise interventions in patients with knee osteoarthritis (OA). We collected data on randomized controlled trials (RCTs) comparing the effects of exercise intervention with those of either nonintervention or psychoeducational intervention in patients with knee OA. Data on pain, stiffness, muscle strength, range of motion, flexibility, maximal oxygen uptake, and position sense were synthesized. The Grading of Recommendations Assessment, Development, and Evaluation system was used to determine the quality of the evidence. Thirty-three RCTs involving 3,192 participants were identified. Meta-analysis provided highquality evidence that exercise intervention improves maximal oxygen uptake, and moderate-quality evidence that exercise intervention also improves pain, stiffness, knee extensor and flexor muscle strength, and position sense. The evidence that exercise intervention improves knee extension and flexion range of motion was deemed as undetermined-quality. In patients with knee OA, improvement in pain, stiffness, muscle strength, maximal oxygen uptake, and position sense with the use of exercise intervention can be expected. Although the quality of evidence of the effect of...Continue Reading

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Citations

Feb 7, 2018·Progress in Rehabilitation Medicine·Ryo Tanaka, Kenta Hirohama
Dec 14, 2018·Journal of General Internal Medicine·Adam PerlmanDavid L Katz

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