Evidence of meningioma infiltration into cranial nerves: clinical implications for cavernous sinus meningiomas

Journal of Neurosurgery
J J LarsonJ M Tew

Abstract

Anatomical and biological studies of cavernous sinus meningiomas help us understand the biological heterogeneity of these tumors. The question of whether cavernous sinus meningiomas infiltrate cranial nerves is clinically important because of the effect on treatment planning. In the authors' experience of treating 36 patients with cavernous sinus meningiomas, tumor invasion into a cranial nerve was documented in two patients in whom a cranial nerve was resected during the cavernous sinus dissection. In both patients, histological examination using hematoxylin and eosin and bodian stains showed infiltration of the cranial nerves by a benign meningioma which, to the best of the authors' knowledge, is a condition previously unreported. This histological finding of meningioma invasion into a cranial nerve demonstrates the biological heterogeneity of cavernous sinus meningiomas and raises concern about the invasive character of meningioma. Because not all tumor cells can be identified radiologically or by direct visualization at surgery, occult tumor infiltration predisposes a patient to recurrence despite the best neurosurgical efforts. Evidence of cranial nerve infiltration by meningioma suggests that, in some circumstances, caver...Continue Reading

References

Apr 1, 1992·Journal of Neurosurgery·R G Ojemann
Jan 1, 1991·Acta neurochirurgica. Supplementum·L N SekharC N Sen
Jan 1, 1983·Journal of Neurosurgery·A B AdegbiteL K Tan
Jun 1, 1983·Journal of Neurosurgery·V Dolenc
Aug 1, 1994·Journal of Neurosurgery·M J KotapkaL N Sekhar
Jul 1, 1993·Brain Pathology·P KleihuesB W Scheithauer
Feb 1, 1957·Journal of Neurology, Neurosurgery, and Psychiatry·D SIMPSON

❮ Previous
Next ❯

Citations

May 27, 2011·Neurosurgical Review·Chien-Min ChenYong-Kwang Tu
Oct 19, 2011·Neurosurgical Review·Ulf WesterlundTiit Mathiesen
Jul 4, 2002·International Journal of Radiation Oncology, Biology, Physics·Antonio NicolatoMassimo Gerosa
Feb 28, 2003·International Journal of Radiation Oncology, Biology, Physics·Bruce E PollockShawn A Schreiner
Apr 1, 1997·Journal of Neurology, Neurosurgery, and Psychiatry·J ZentnerJ Schramm
Sep 22, 2009·Journal of Neurosurgery·Jonathan M BledsoeBruce E Pollock
Jul 3, 2013·Journal of Neurosurgery·Bruce E PollockRobert L Foote
Dec 3, 2013·Neurosurgical Focus·Daniel R KlingerSamuel L Barnett
Oct 27, 2007·Neurosurgical Focus·Laurence DavidsonSteven L Giannotta
Apr 15, 1997·Neurosurgical Focus·M A LefkowitzW T Couldwell
Jan 27, 2005·Neurosurgical Focus·Rodrigo Couto TorresMichael Selch
Aug 19, 2007·Journal of Neurosurgery·Aurelia KollováLadislava Janousková
Oct 17, 2007·Journal of Neurosurgery·Toshinori HasegawaDai Ishii
Nov 6, 2007·Journal of Neurosurgery·Marc SindouThomas Lieutaud
Jul 24, 2002·Journal of Neurosurgery·John Y K LeeL Dade Lunsford
Jan 24, 2007·Journal of Neurosurgery·William T CouldwellOssama Al-Mefty
Jun 12, 2002·Lancet·Daniela VaideanuJ P Deady
Oct 8, 2013·Neurosurgery Clinics of North America·Bruce E PollockMichael J Link
May 29, 2012·World Neurosurgery·David W Andrews, Christopher J Farrell
Nov 29, 2011·World Neurosurgery·Salvatore Di MaioLaligam N Sekhar
Sep 8, 2010·Hematology/oncology Clinics of North America·Meg R GerstenblithMargaret A Tucker
Oct 12, 2010·Clinical Radiology·Y TangT Wilhelm
Feb 6, 2010·International Journal of Radiation Oncology, Biology, Physics·Philippe MetellusDanielle Rigamonti
Sep 16, 2009·Otolaryngologic Clinics of North America·John M McGregor, Atom Sarkar
May 30, 2009·Lancet·Ashok R AsthagiriRussell R Lonser
Jun 17, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Louise GormanMichael Dally
May 10, 2008·Neuroimaging Clinics of North America·Minerva BeckerJacqueline Delavelle
Oct 27, 2015·CNS Oncology·Debebe TheodrosChetan Bettegowda
Apr 20, 2004·International Journal of Radiation Oncology, Biology, Physics·Michael T SelchAntonio A F Desalles
Nov 29, 2015·Otolaryngologic Clinics of North America·Damien BressonSébastien Froelich
Aug 9, 2015·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Mustafa El-KhatibMohammad Maarouf
Jun 29, 2005·Seminars in Radiation Oncology·Philippe GiraudKenneth E Rosenzweig
Jul 5, 2005·Surgical Neurology·Florian RoserMadjid Samii
Jul 21, 2005·International Journal of Radiation Oncology, Biology, Physics·Bruce E Pollock, Scott L Stafford
Sep 3, 2013·World Neurosurgery·William T CouldwellPhilipp Taussky
Oct 29, 2004·Neurosurgery·Keisuke MaruyamaTakaaki Kirino
Nov 26, 2002·Neurosurgery·Roberto SpiegelmannM Raphael Pfeffer

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
surgical resection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.