Evidence of the synergistic interaction of honey bee pathogens Nosema ceranae and Deformed wing virus

Veterinary Microbiology
Huoqing ZhengYan Ping Chen

Abstract

Nosema ceranae and Deformed wing virus (DWV) are two of the most prevalent pathogens currently attacking Western honey bees, Apis mellifera, and often simultaneously infect the same hosts. Here we investigated the effect of N. ceranae and Deformed wing virus (DWV) interactions on infected honey bees under lab conditions and at different nutrition statuses. Our results showed that Nosema could accelerate DWV replication in infected bees in a dose-dependent manner at the early stages of DWV infection. When bees were restricted from pollen nutrition, inoculation with 1×10(4) and 1×10(5) spores/bee could cause a significant increase in DWV titer, while inoculation with 1×10(3) spores/bee did not show any significant effect on the DWV titer. When bees were provided with pollen, only inoculation with 1×10(5) spores/bee showed significant effect on DWV titer. However, our results also showed that the two pathogens did not act synergistically when the titer of DWV reached a plateau. This study suggests that the synergistic effect of N. ceranae and DWV is dosage- and nutrition-dependent and that the synergistic interactions between the two pathogens could have implications on honey bee colony losses.

References

May 18, 2005·Proceedings of the National Academy of Sciences of the United States of America·Xiaolong Yang, Diana L Cox-Foster
Apr 1, 2006·Journal of Invertebrate Pathology·Mariano HigesAránzazu Meana
Jul 27, 2007·Journal of Invertebrate Pathology·Mariano HigesAránzazu Meana
Jul 24, 2008·Environmental Microbiology·Mariano HigesAránzazu Meana
May 27, 2009·Journal of Invertebrate Pathology·Yanping ChenJeffery S Pettis
Nov 17, 2009·Journal of Invertebrate Pathology·Ingemar Fries
Jan 7, 2010·Environmental Microbiology·Cédric AlauxYves Le Conte
Jan 22, 2010·Biology Letters·Cédric AlauxYves Le Conte
Mar 17, 2010·Applied and Environmental Microbiology·Sebastian GisderElke Genersch
Nov 9, 2011·Journal of Invertebrate Pathology·Hongxia AiRichou Han
Jan 17, 2012·Die Naturwissenschaften·Jeffery S PettisGalen Dively
Mar 3, 2012·PloS One·Benjamin DainatPeter Neumann
May 23, 2012·Journal of Insect Physiology·Veeranan ChaimaneeJeffery S Pettis
Jun 9, 2012·Science·Stephen J MartinDeclan C Schroeder
Nov 17, 2012·Virulence·Declan C Schroeder, Stephen J Martin
Dec 29, 2012·Journal of Invertebrate Pathology·Benjamin Dainat, Peter Neumann
Apr 1, 2009·Environmental Microbiology Reports·Mariano HigesJosé L Bernal
Jul 19, 2013·Environmental Microbiology Reports·Stephen J MartinMariano Higes

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Citations

Mar 27, 2018·Environmental Microbiology·Raquel Martín-HernándezMariano Higes
Jun 12, 2019·Annual Review of Virology·Stephen J Martin, Laura E Brettell
May 17, 2018·Frontiers in Microbiology·Guilin LiXingqi Guo

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