Aug 1, 1989

Evidence that chicken CR1 elements represent a novel family of retroposons

Molecular and Cellular Biology
R Silva, J B Burch

Abstract

We report the first precise delineation of a chicken CR1 element and show that it is flanked by a 6-base-pair target site duplication that occurred when this repetitive element transposed. The 3' end of this CR1 element is defined by an 8-base-pair imperfect direct repeat, and we infer that this sequence represents the 3' end of all intact CR1 elements. In contrast, the 5' ends are not unique, and we argue that this variation existed at the time each element transposed. We also provide evidence that CR1 elements transposed into preferred target sites. CR1 elements therefore appear to represent a novel class of passive retroposons.

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Mentioned in this Paper

Direct Repeat
Repetitive Region
Selfish DNA
Vitellogenin II
Homologous Sequences, Nucleic Acid
Retroposons
Gene Duplication Abnormality
Introns
RNA-Directed DNA Polymerase
DNA Transposons

About this Paper

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