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Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell

British Journal of Haematology

May 1, 1994

Marleen H C BakkusK Thielemans

PMID: 7947257

Abstract

There is still much controversy about the precursor cell type in multiple myeloma (MM). Some authors claim that it is a pre-B cell, others state that it is a memory B cell or plasmablast. We have recently shown that the VDJ region of the MM immunoglobulin heavy chain gene is somatically...read more

Mentioned in this Paper

Immunoglobulin Activity
CD19 Expressing Cell Count
Peripheral Blood
Pre-B Lymphocytes
Somatic Mutation
CD19 Antigens
Bone Marrow
SLC3A2 gene
Plasmablast (Cell)
Immunoglobulin Isotypes
Paper Details
References
  • References17
  • Citations69
12
  • References17
  • Citations69
12345...

Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell

British Journal of Haematology

May 1, 1994

Marleen H C BakkusK Thielemans

PMID: 7947257

DOI:

Abstract

There is still much controversy about the precursor cell type in multiple myeloma (MM). Some authors claim that it is a pre-B cell, others state that it is a memory B cell or plasmablast. We have recently shown that the VDJ region of the MM immunoglobulin heavy chain gene is somatically...read more

Mentioned in this Paper

Immunoglobulin Activity
CD19 Expressing Cell Count
Peripheral Blood
Pre-B Lymphocytes
Somatic Mutation
CD19 Antigens
Bone Marrow
SLC3A2 gene
Plasmablast (Cell)
Immunoglobulin Isotypes

Related Papers

Paper Details
References
  • References17
  • Citations69
12
  • References17
  • Citations69
12345...
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