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Evidences of a cytotoxic activity of S-adenosylmethionine on OCI-AML3 cells

bioRxiv

May 8, 2014

Kathrin Aprile von HohenstaufenBarbara De Servi

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Abstract

Background. The acute myeloid leukemia (AML) cell line OCI-AML3, carrying both NPM1 mutation A and the heterozygous DNMT3A R882C mutation, represents the model for in vitro studies on AML with mutated NPM1. AML with mutated NPM1 harbours a hypo-methylated profile distinct from those of ...read more

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Propidium
Enzymes, antithrombotic
Tetrazolium Salts
Enzymes, peripheral vasodilators
Antineoplastic Agents
Mutant
RUNX2 gene
Wiskott-Aldrich Syndrome
NPM1 Gene Mutation
DNMT1 gene
1
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  • Evidences of a cytotoxic activity of S-adenosylmethionine on OCI-AML3 cells

    bioRxiv

    May 8, 2014

    Kathrin Aprile von HohenstaufenBarbara De Servi

    PMID: 990004978

    DOI: 10.1101/004978

    Abstract

    Background. The acute myeloid leukemia (AML) cell line OCI-AML3, carrying both NPM1 mutation A and the heterozygous DNMT3A R882C mutation, represents the model for in vitro studies on AML with mutated NPM1. AML with mutated NPM1 harbours a hypo-methylated profile distinct from those of ...read more

    Mentioned in this Paper

    Propidium
    Enzymes, antithrombotic
    Tetrazolium Salts
    Enzymes, peripheral vasodilators
    Antineoplastic Agents
    1

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