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Evidences of a cytotoxic activity of S-adenosylmethionine on OCI-AML3 cells

bioRxiv

May 8, 2014

Kathrin Aprile von HohenstaufenBarbara De Servi

Abstract

Background The acute myeloid leukemia (AML) cell line OCI-AML3, carrying both NPM1 mutation A and the heterozygous DNMT3A R882C mutation, represents the model for in vitro studies on AML with mutated NPM1[1][1]. AML with mutated NPM1 harbours a hypo-methylated profile distinct from thos...read more

Mentioned in this Paper

DNMT1 gene
DNMT3A gene
RUNX2 gene
Cytotoxicity Assay
Bromides Measurement
Angiomyolipoma
Intravenous Infusion Procedures
Assay
Hepatocellular Carcinoma of the Mouse
NOD.CB17-Prkdc-scid/J Mouse
1
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Evidences of a cytotoxic activity of S-adenosylmethionine on OCI-AML3 cells

bioRxiv

May 8, 2014

Kathrin Aprile von HohenstaufenBarbara De Servi

PMID: 990004978

DOI: 10.1101/004978

Abstract

Background The acute myeloid leukemia (AML) cell line OCI-AML3, carrying both NPM1 mutation A and the heterozygous DNMT3A R882C mutation, represents the model for in vitro studies on AML with mutated NPM1[1][1]. AML with mutated NPM1 harbours a hypo-methylated profile distinct from thos...read more

Mentioned in this Paper

DNMT1 gene
DNMT3A gene
RUNX2 gene
Cytotoxicity Assay
Bromides Measurement
Angiomyolipoma
Intravenous Infusion Procedures
Assay
Hepatocellular Carcinoma of the Mouse
NOD.CB17-Prkdc-scid/J Mouse
1

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