Evolution and population genomics of the Lyme borreliosis pathogen, Borrelia burgdorferi

Trends in Genetics : TIG
Stephanie N SeifertDustin Brisson

Abstract

Population genomic studies have the potential to address many unresolved questions about microbial pathogens by facilitating the identification of genes underlying ecologically important traits, such as novel virulence factors and adaptations to humans or other host species. Additionally, this framework improves estimations of population demography and evolutionary history to accurately reconstruct recent epidemics and identify the molecular and environmental factors that resulted in the outbreak. The Lyme disease bacterium, Borrelia burgdorferi, exemplifies the power and promise of the application of population genomics to microbial pathogens. We discuss here the future of evolutionary studies in B. burgdorferi, focusing on the primary evolutionary forces of horizontal gene transfer, natural selection, and migration, as investigations transition from analyses of single genes to genomes.

References

Nov 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·D E DykhuizenB J Luft
May 15, 1998·Molecular Biology and Evolution·J Maynard Smith, N H Smith
Nov 21, 2000·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J M SmithN H Smith
Dec 6, 2000·Proceedings of the National Academy of Sciences of the United States of America·J E Purser, S J Norris
Jul 4, 2001·Trends in Microbiology·D E Dykhuizen, G Baranton
Jul 12, 2001·Proceedings of the National Academy of Sciences of the United States of America·J R FitzgeraldJ M Musser
Nov 25, 2003·Nature Reviews. Genetics·Gordon LuikartPierre Taberlet
Apr 16, 2004·The Journal of Clinical Investigation·Allen C SteereLisa Glickstein
Oct 30, 2004·Genetics·Dustin Brisson, Daniel E Dykhuizen
May 28, 2005·Science·Stephen I WrightBrandon S Gaut
Mar 4, 2006·Microbes and Infection·Vanessa LagalGuy Baranton
Apr 6, 2006·International Journal of Systematic and Evolutionary Microbiology·Dania RichterGuy Baranton
May 18, 2006·Emerging Infectious Diseases·Klára HanincováDurland Fish
May 18, 2006·Emerging Infectious Diseases·Xinzhi ZhangAlan D Fix
Aug 9, 2006·Nature Reviews. Microbiology·Klaus KurtenbachNicholas H Ogden
Oct 20, 2006·Current Opinion in Genetics & Development·Garrett Hellenthal, Matthew Stephens
Apr 11, 2008·Molecular Microbiology·Justin D Radolf, Melissa J Caimano
Jun 25, 2008·Proceedings of the National Academy of Sciences of the United States of America·Gabriele MargosKlaus Kurtenbach
Oct 31, 2008·Ecology·Kathleen LoGiudiceRichard S Ostfeld
May 26, 2009·Trends in Microbiology·Michiel Vos
Jun 23, 2009·Applied and Environmental Microbiology·Gabriele MargosKlaus Kurtenbach
Aug 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Anne Gatewood HoenDurland Fish
Apr 17, 2010·Evolution; International Journal of Organic Evolution·Parris T HumphreyDustin Brisson
May 29, 2010·Emerging Infectious Diseases·Dustin BrissonDaniel E Dykhuizen
Jun 12, 2010·Annual Review of Microbiology·George Chaconas, Kerri Kobryn
Aug 28, 2010·Bioinformatics·Darren P MartinPierre Lefeuvre
Oct 13, 2010·Proceedings of the National Academy of Sciences of the United States of America·Maureen L Coleman, Sallie W Chisholm
Nov 3, 2010·Nature Genetics·Giovanna MorelliMark Achtman
Dec 24, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A CascioG Pappas
Jan 11, 2011·International Journal of Plant Sciences·Paul A HohenloheWilliam A Cresko
Feb 15, 2011·Applied and Environmental Microbiology·Helvécio D Coletta-FilhoRodrigo P P Almeida

❮ Previous
Next ❯

Citations

Oct 4, 2017·Future Microbiology·Bilal AslamMuhammad Khalid Farooq Salamat
Aug 25, 2015·Applied and Environmental Microbiology·N H OgdenT J Moriarty
Jan 18, 2018·Nature Ecology & Evolution·Emiko B SanoScott R Miller
Apr 4, 2018·Proceedings of the National Academy of Sciences of the United States of America·Quentin BernardUtpal Pal
Dec 19, 2018·Frontiers in Neurology·Enea Gino Di DomenicoFabrizio Ensoli
Oct 1, 2020·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Kayleigh R O'KeeffeDustin Brisson
Jun 24, 2021·Ticks and Tick-borne Diseases·Katherine A WolcottNoémie S Becker
Jul 3, 2021·Brain Sciences·Lenzie Ford, Danielle M Tufts
Feb 1, 2018·Frontiers in Ecology and Evolution·Dustin Brisson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Related Papers

Verhandlungen der Deutschen Gesellschaft für Innere Medizin
Peter Herzer
Pediatrics in Review
Eugene D Shapiro
Journal of the American Veterinary Medical Association
J E Madigan, J Teitler
© 2021 Meta ULC. All rights reserved