Abstract
We obtained a series of methicillin-resistant Staphylococcus aureus isolates, including both daptomycin-susceptible strain TD1 and daptomycin-resistant strain TD4, from a patient. We determined the complete genome sequences of TD1 and TD4 using next-generation sequencing, and only four single-nucleotide polymorphisms (SNPs) were identified, one each in capB (E58K), rpoB (H481Y), lytN (I16V), and mprF (V351E). We determined that these four SNPs were sufficient to cause the strains to develop daptomycin, vancomycin, and rifampin resistance.
References
Mar 4, 2000·Journal of Clinical Microbiology·M C EnrightB G Spratt
May 7, 2002·The Journal of Infectious Diseases·Takayuki YamaguchiMotoyuki Sugai
Sep 14, 2002·Infection and Immunity·Takayuki YamaguchiMotoyuki Sugai
Nov 8, 2003·Journal of Clinical Microbiology·Linda K McDougalFred C Tenover
Mar 7, 2006·Lancet·Binh An DiepFrançoise Perdreau-Remington
May 26, 2006·Antimicrobial Agents and Chemotherapy·Lisa FriedmanJared A Silverman
Oct 18, 2006·Antimicrobial Agents and Chemotherapy·Yoko KondoKeiichi Hiramatsu
Oct 20, 2006·Journal of Clinical Microbiology·Xiao Xue MaKeiichi Hiramatsu
Jan 1, 2008·Infection·M HentschkeH Rohde
Apr 28, 2009·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Ivan RevaTatsuo Yamamoto
Jul 13, 2011·Antimicrobial Agents and Chemotherapy·Miki MatsuoKeiichi Hiramatsu
Sep 21, 2011·Immunogenetics·Yuki F KitaTakashi Shiina
Mar 31, 2012·Journal of Clinical Microbiology·Ulrich VogelDag Harmsen
Dec 12, 2012·Annals of the New York Academy of Sciences·Arnold S BayerHans-Georg Sahl
Aug 27, 2013·PloS One·Yan ChenMichael Otto
Oct 11, 2013·The Journal of Antimicrobial Chemotherapy·O GaschUNKNOWN REIPI/GEIH study groups
Jun 7, 2014·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·C H ShiboskiUNKNOWN AIDS Clinical Trials Group Network and Oral HIV/AIDS Research Alliance
Jul 2, 2014·The Journal of Clinical Investigation·Susana Gardete, Alexander Tomasz
Aug 26, 2014·BMC Infectious Diseases·Ayaka TsukimoriTetsuya Matsumoto
Citations
Jun 9, 2017·The Journal of Antimicrobial Chemotherapy·Jin Yang BaekJae-Hoon Song
Dec 12, 2017·PLoS Neglected Tropical Diseases·Cedar L MitchellDawn N Birdsell
Jun 22, 2018·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Gi Yong LeeSoo-Jin Yang
Aug 18, 2017·RNA Biology·Rachel N Fields, Hervé Roy
May 29, 2019·Journal of Medical Microbiology·M D S BascoM E Hart
Sep 3, 2019·Frontiers in Microbiology·Makoto KurodaHideaki Hanaki
Sep 23, 2020·Antimicrobial Agents and Chemotherapy·Itaru NakamuraHidehiro Watanabe
Apr 23, 2020·Enfermedades infecciosas y microbiología clínica·Alejandra AsenjoJuan-Ignacio Alós
Jun 6, 2021·Enfermedades Infecciosas Y Microbiologia Clinica·Alejandra AsenjoJuan-Ignacio Alós