Evolution of a genetic code simulated with the computer

Origins of Life
H Kuhn, C Kuhn

Abstract

A simple selforganizing model system of molecules is considered and it is demonstrated by a computer simulation, that a genetic code of 16 elements (aminoacids) can gradually be formed by such a system in the course of many generations. By a number of rare chance events, each suppressing other events of equal a priori probability, a single code results out of an immense number of possible codes of the same a priori probability. The result is discussed in relation to the uniqueness of the genetic code in living systems. The computer simulation emphasizes a particular step in a model pathway discussed elsewhere consisting of many assumed physicochemical steps leading to a genetic apparatus.

References

Dec 1, 1976·Origins of Life·F H CrickG Pieczenik
Sep 1, 1972·Angewandte Chemie·H D FörsterlingK H Tews
Jan 1, 1969·Die Naturwissenschaften·S W Fox

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Citations

Mar 1, 1982·Origins of Life·R R Kocherlakota, N D Acland
Jan 1, 1988·Journal of Molecular Evolution·L F Abbott
Jan 1, 1980·Bio Systems·A I Oparin, K L Gladilin
Jul 19, 2001·Proceedings of the National Academy of Sciences of the United States of America·C Kuhn

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