Evolution of aortic wall thickness and stiffness with atherosclerosis: long-term follow up from the multi-ethnic study of atherosclerosis

Hypertension
Chia-Ying LiuW Gregory Hundley

Abstract

The study was performed to determine age, sex, and time-dependent changes in aortic wall thickness (AWT) and to evaluate cross-sectional associations between AWT and arterial stiffness in older adults. Three hundred seventy-one longitudinal and 426 cross-sectional measurements of AWT from cardiovascular magnetic resonance imaging studies conducted within the Multi-Ethnic Study of Atherosclerosis were analyzed at 2 points in time, in 2000 to 2002 and then again from follow-up examinations in 2010 to 2012. Aortic wall thickness was determined from a double inversion recovery black-blood fast spin-echo sequence, and aortic stiffness was measured from a phase-contrast cine gradient echo sequence. The thickness of the midthoracic descending aortic wall was measured and correlated to distensibility of the ascending aorta and aortic pulse wave velocity. The average rate of AWT change was 0.032 mm/y. The increase in AWT was greater for those aged 45 to 54 years relative to individuals older than 55 years (P trend<0.001). Ascending aortic distensibility was lower (P<0.001) and pulse wave velocity was higher (P=0.012) for hypertensive subjects. After adjustment for traditional risk factors, distensibility of the ascending aorta was signi...Continue Reading

References

Oct 25, 2002·American Journal of Epidemiology·Diane E BildRussell P Tracy
Jun 21, 2003·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·M LudwigK O Stumpe
Feb 8, 2006·Circulation·Francesco U S Mattace-RasoJacqueline C M Witteman
Jan 8, 2011·Journal of Vascular Surgery·Eric B RoseroCarlos H Timaran

❮ Previous
Next ❯

Citations

Oct 1, 2016·American Journal of Hypertension·Chong-Fu JiaZhao-Qian Wang
Sep 29, 2017·Physiological Reviews·Patrick LacolleyStéphane Laurent
Mar 18, 2015·Hypertension·Sophie I MavrogeniGenovefa Kolovou
Apr 15, 2018·Circulation. Cardiovascular Imaging·Yoshiaki OhyamaJoao A C Lima
Jul 11, 2020·Journal of the American Heart Association·Shannon K ParrCarl J Ade
Aug 7, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Jacob W GroenendykNehal N Mehta
Jul 20, 2017·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Kihei YoneyamaJoão A C Lima
May 10, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Wenjin LiuChun Yuan
Jul 25, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Barry Doyle, UNKNOWN All The Authors
Nov 28, 2017·Translational Research : the Journal of Laboratory and Clinical Medicine·Ahmad F HedayatLilach O Lerman
Mar 23, 2021·Advanced Science·Morgan AlmanzaYves Perriard
May 25, 2021·Hypertension·Benard O OgolaSarah H Lindsey
Oct 6, 2021·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Mamoru ArakawaAtsushi Yamaguchi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Related Papers

Diabetes Care
Evrim B TurkbeyDiabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group
Journal of Vascular and Interventional Radiology : JVIR
Roberto LorbeerBirger Mensel
© 2021 Meta ULC. All rights reserved