Evolution of dilated cardiomyopathy (DCM) from idiopathic hypertrophic cardiomyopathy (IHCM) vs. inflammatory dilated cardiomyopathy (DCMi): a rare case of sudden death in an 8-year-old boy

Pathology, Research and Practice
Reinhard DettmeyerBurkhard Madea

Abstract

In rare cases, the diagnosis of hypertrophic and dilated cardiomyopathy (DCM) in children was established postmortem. Our case report deals with the sudden and unexpected death of an 8-year-old boy. The postmortem examination revealed non-obstructive hypertrophy with irregular arrangement of muscular fibers, dilatation of the ventricles, endocardial fibrosis, microfocal vacuolization with enlarged hyperchromatic nuclei, and signs of inflammation with interstitial fibrosis. We present an evolution from idiopathic cardiomyopathy to DCM. To some extent, there were morphologic signs of an inflammatory process that first led us to suspect a specific inflammatory DCM.

References

Mar 1, 1981·The American Journal of Cardiology·V FusterR L Frye
Sep 1, 1994·British Heart Journal·M BurchJ E Deanfield
Jan 1, 1994·Circulation·R Roberts
Oct 15, 1996·Circulation·M L SchwartzS E Lipshultz
Jun 1, 1999·Cardiology in Review·R M Bryant

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Citations

Nov 26, 2009·Forensic Science International : Synergy·R B Dettmeyer, R Kandolf
Jul 16, 2015·Journal of Cheminformatics·Gang FuEvan Bolton
Mar 26, 2005·Immunology Letters·José Manuel Rodríguez-PérezGilberto Vargas-Alarcón
Apr 15, 2014·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·H J FengM J Zhou

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