PMID: 8610172Apr 2, 1996Paper

Evolution of GABAergic circuitry in the mammalian medial geniculate body

Proceedings of the National Academy of Sciences of the United States of America
J A Winer, D T Larue

Abstract

Many features in the mammalian sensory thalamus, such as the types of neurons, their connections, or their neurotransmitters, are conserved in evolution. We found a wide range in the proportion of gamma-aminobutyric acidergic (GABAergic) neurons in the medial geniculate body, from <1% (bat and rat) to 25% or more (cat and monkey). In the bat, some medial geniculate body subdivisions have no GABAergic cells. Species-specific variation also occurs in the somesthetic ventrobasal complex. In contrast, the lateral geniculate body of the visual system has about the same proportion of GABAergic cells in many species. In the central auditory pathway, only the medial geniculate body shows this arrangement; the relative number of GABAergic cells in the inferior colliculus and auditory cortex is similar in each species. The range in the proportion of GABAergic neurons suggests that there are comparative differences in the neural circuitry for thalamic inhibition. We conclude that the number of GABAergic neurons in thalamic sensory nuclei may have evolved independently or divergently in phylogeny. Perhaps these adaptations reflect neurobehavioral requirements for more complex, less stereotyped processing, as in speech-like communication.

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Citations

Mar 14, 2002·The Journal of Comparative Neurology·Justin S CetasNathaniel T McMullen
Jun 10, 2011·Brain Structure & Function·Ladislav OudaJosef Syka
May 13, 1999·Hearing Research·J A WinerD T Larue
Jul 23, 1996·Proceedings of the National Academy of Sciences of the United States of America·J A WinerD L Oliver
Feb 8, 2011·PloS One·Ben D RichardsonDonald M Caspary
Jan 18, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ben D RichardsonDonald M Caspary
Dec 24, 2003·Proceedings of the National Academy of Sciences of the United States of America·D M MooneyB Hu
Mar 13, 2012·Brain Research·Ben D RichardsonDonald M Caspary
Oct 27, 2015·Anatomical Science International·Tetsufumi ItoDouglas L Oliver
Nov 20, 2015·Frontiers in Neural Circuits·Charles C Lee
May 1, 2007·Journal of Chemical Neuroanatomy·Raphael Pinaud, Claudio V Mello
Mar 24, 2006·Hearing Research·Jeffery A Winer
Aug 11, 2005·Hearing Research·Jeffery A Winer
Jan 30, 2015·Cell and Tissue Research·Ladislav OudaJosef Syka
Jun 26, 2012·Brain and Language·Charles C Lee
Nov 12, 2014·Frontiers in Neurology·Benjamin D AuerbachRichard J Salvi
Feb 7, 2016·The Journal of Comparative Neurology·Tetsufumi Ito, Yasuro Atoji

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