Evolution of genes on the Salmonella Virulence plasmid phylogeny revealed from sequencing of the virulence plasmids of S. enterica serotype Dublin and comparative analysis

Genomics
Chishih ChuCheng-Hsun Chiu

Abstract

Salmonella enterica serotype Dublin harbors an approximately 80-kb virulence plasmid (pSDV), which mediates systemic infection in cattle. There are two types of pSDV: one is pSDVu (pOU1113) in strain OU7025 and the other pSDVr (pOU1115) in OU7409 (SD Lane) and many clinical isolates. Sequence analysis showed that pSDVr was a recombinant plasmid (co-integrate) of pSDVu and a plasmid similar to a 35-kb indigenous plasmid (pOU1114) of S. Dublin. Most of the F-transfer region in pSDVu was replaced by a DNA segment from the pOU1114-like plasmid containing an extra replicon and a pilX operon encoding for a type IV secretion system to form pSDVr. We reconstructed the particular evolutionary history of the seven virulence plasmids of Salmonella by comparative sequence analysis. The whole evolutionary process might begin with two different F-like plasmids (IncFI and IncFII), which then incorporated the spv operon and fimbriae operon from the chromosome to form the primitive virulence plasmids. Subsequently, these plasmids descended by deletion from a relatively large plasmid to smaller ones, with some recombination events occurring over time. Our results suggest that the phylogeny of virulence plasmids as a result of frequent recombinat...Continue Reading

References

Dec 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·F C FangD G Guiney
May 1, 1991·Medicine·F C Fang, J Fierer
Mar 1, 1981·Journal of Bacteriology·C I Kado, S T Liu
Mar 1, 1993·Molecular Microbiology·P A GuligM Rhen
Aug 10, 2002·Journal of Bacteriology·Lishan ChenEugene W Nester
Apr 5, 2005·Journal of Bacteriology·Timothy J G FothergillFinbarr Hayes
Nov 24, 2005·Veterinary Microbiology·I RychlikH Hradecka

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Citations

Jun 3, 2014·BMC Genomics·Nathan L BachmannScott A Beatson
May 20, 2009·Antimicrobial Agents and Chemotherapy·Marina CerquettiAlessandra Carattoli
Sep 1, 2009·Applied and Environmental Microbiology·Cheryl-Lynn Y OngMark A Schembri
Mar 28, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Ye FengShu-Lin Liu
Dec 8, 2010·Vaccine·Hyuk-Joon Kwon, Sun-Hee Cho
Dec 4, 2013·Microbiology and Molecular Biology Reviews : MMBR·Steven L FoleyJessica Danzeisen
Mar 23, 2017·Antimicrobial Agents and Chemotherapy·Chand S MangatMichael R Mulvey
Nov 15, 2011·Journal of Bacteriology·John StavrinidesDavid S Guttman
Oct 18, 2018·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Vanesa GarcíaM Rosario Rodicio
May 1, 2019·Antimicrobial Agents and Chemotherapy·Chand S MangatUNKNOWN Canadian Integrated Program for Antimicrobial Resistance Surveillance Public Health Partnership

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