PMID: 8945069Nov 1, 1996Paper

Evolution of late potentials during the first 8 hours of myocardial infarction treated with thrombolysis

Pacing and Clinical Electrophysiology : PACE
W PetersM Meesmann

Abstract

It has been demonstrated that successful thrombolytic therapy is associated with a reduction of late potentials in the signal-averaged electrocardiogram (SAECG) recorded within 48 hours after hospital admission. This study extends these observations, using for the first time a longitudinal design investigating whether ischemia and its potential reversal by thrombolytic therapy are associated with dynamic changes in SAECG recordings obtained continuously for 8 hours after the start of therapy in patients with acute myocardial infarction (MI). SAECGs were obtained from 12 patients (2 women and 10 men; ages 63 +/- 13 years) with acute MI. The SAECG (X2 + Y2 + Z2)1/2 was generated with a high pass filter of 40 Hz, noise < or = 0.3 microV. Comparing the SAECG recordings during the first and eighth hours, there was a significant decrease in filtered QRS duration (fQRS; 119.5 +/- 17.1 vs 106.3 +/- 15.3 ms) and duration of the low amplitude signals < or = 40 microV of the terminal QRS (LAS40; 48.8 +/- 18 vs 34.2 +/- 14.2 ms), and increase of root mean square voltage of the last 40 ms of the QRS (t-RMS; 14.8 +/- 9.3 vs 37.8 +/- 34.4 microV) (rank test, P < or = 0.05). In this patient series, there was a significant improvement of fQRS, ...Continue Reading

References

Dec 1, 1992·Pacing and Clinical Electrophysiology : PACE·D A RubinM B Weiss
Apr 1, 1991·The American Journal of Cardiology·G TurittoN el-Sherif
Jul 1, 1990·The American Journal of Cardiology·E B CarefN el-Sherif
Mar 1, 1989·The Journal of Emergency Medicine·K Gordon

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Citations

Aug 9, 2002·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Namik Kemal EryolServet Cetin

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