Abstract
Recently, it has been assumed that resistance of Plasmodium to chloroquine increased malaria mortality. The study aimed to assess the impact of chemoresistance on mortality attributable to malaria in a rural area of Senegal, since the emergence of resistance in 1992, whilst chloroquine was used as first-line treatment of malaria, until the change in national anti-malarial policy in 2003. The retrospective study took place in the demographic surveillance site (DSS) of Niakhar. Data about malaria morbidity were obtained from health records of three health care facilities, where diagnosis of malaria was based on clinical signs. Source of data concerning malaria mortality were verbal autopsies performed by trained fieldworkers and examined by physicians who identified the probable cause of death. From 1992 to 2004, clinical malaria morbidity represented 39% of total morbidity in health centres. Mean malaria mortality was 2.4 per thousand and 10.4 per thousand among total population and children younger than five years, respectively, and was highest in the 1992-1995 period. It tended to decline from 1992 to 2003 (Trend test, total population p = 0.03, children 0-4 years p = 0.12 - children 1-4 years p = 0.04- children 5-9 years p = ...Continue Reading
References
Aug 8, 1992·Lancet·R W SnowK Marsh
Nov 1, 1991·Transactions of the Royal Society of Tropical Medicine and Hygiene·M OlivarL Loutan
Jun 1, 1990·International Journal of Epidemiology·H D KalterS A Gultiano
Nov 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·J F TrapeJ Le Bras
Jul 10, 1998·Tropical Medicine & International Health : TM & IH·D ChandramohanR J Hayes
Sep 15, 1998·Tropical Medicine & International Health : TM & IH·V RobertD Fontenille
Oct 14, 1998·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·J F TrapeF Simondon
Oct 24, 1998·The Journal of Antimicrobial Chemotherapy·B PradinesJ C Doury
Aug 18, 1999·Archives of Disease in Childhood·L MuheM W Weber
Sep 2, 1999·Tropical Medicine & International Health : TM & IH·N White
Jun 26, 2001·Tropical Medicine & International Health : TM & IH·F FontP L Alonso
Jun 27, 2001·The American Journal of Tropical Medicine and Hygiene·J F Trape
Oct 5, 2001·Parasite : Journal De La Société Française De Parasitologie·C S SokhnaV Robert
Feb 1, 2002·International Journal of Epidemiology·V DelaunayF Simondon
Jun 5, 2003·The Lancet Infectious Diseases·Eline L KorenrompRobert W Snow
Dec 1, 2004·International Journal of Epidemiology·Jean-François EtardValérie Delaunay
Mar 1, 2006·Lancet·Badara CisséJean-François Trape
Apr 4, 2006·Bulletin of the World Health Organization·Martin AdjuikFred Binka
Apr 12, 2006·Parasite : Journal De La Société Française De Parasitologie·N ValinA Garcia
Nov 4, 2006·The Journal of Infectious Diseases·Snehal N ShahMary J Hamel
Jan 11, 2007·Studies in Family Planning
Jan 24, 2008·PloS One·Cheikh SokhnaJean-François Trape
Feb 28, 2008·Malaria Journal·Caterina GuinovartPedro L Alonso
Jun 14, 2008·Journal of Biosocial Science·Aurélien Franckel, Richard Lalou
Apr 28, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·A MunierJ P Chippaux
Apr 29, 2009·Malaria Journal·Aline MunierJean-Philippe Chippaux
Dec 1, 2009·Malaria Journal·Aline MunierJean-Philippe Chippaux
Sep 8, 2010·Malaria Journal·Vanessa MachaultChristophe Rogier
Mar 20, 2013·Revue D'épidémiologie Et De Santé Publique·A FayeA Tal-Dia
Citations
Aug 14, 2009·PloS One·Ricardo AguasLisa J White
May 3, 2013·PloS One·Emelda A OkiroRobert W Snow
Jul 20, 2010·The Lancet Infectious Diseases·Wendy Prudhomme O'MearaBrian Greenwood
Dec 1, 2009·Malaria Journal·Aline MunierJean-Philippe Chippaux
Jan 29, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Aldiouma DialloJohn C Victor
Jul 26, 2021·Free Radical Biology & Medicine·Rafael Cardoso Maciel Costa SilvaMarcelo Torres Bozza