Evolution of malaria mortality and morbidity after the emergence of chloroquine resistance in Niakhar, Senegal.

Malaria Journal
Aline MunierJean-Philippe Chippaux

Abstract

Recently, it has been assumed that resistance of Plasmodium to chloroquine increased malaria mortality. The study aimed to assess the impact of chemoresistance on mortality attributable to malaria in a rural area of Senegal, since the emergence of resistance in 1992, whilst chloroquine was used as first-line treatment of malaria, until the change in national anti-malarial policy in 2003. The retrospective study took place in the demographic surveillance site (DSS) of Niakhar. Data about malaria morbidity were obtained from health records of three health care facilities, where diagnosis of malaria was based on clinical signs. Source of data concerning malaria mortality were verbal autopsies performed by trained fieldworkers and examined by physicians who identified the probable cause of death. From 1992 to 2004, clinical malaria morbidity represented 39% of total morbidity in health centres. Mean malaria mortality was 2.4 per thousand and 10.4 per thousand among total population and children younger than five years, respectively, and was highest in the 1992-1995 period. It tended to decline from 1992 to 2003 (Trend test, total population p = 0.03, children 0-4 years p = 0.12 - children 1-4 years p = 0.04- children 5-9 years p = ...Continue Reading

References

Nov 1, 1991·Transactions of the Royal Society of Tropical Medicine and Hygiene·M OlivarL Loutan
Jun 1, 1990·International Journal of Epidemiology·H D KalterS A Gultiano
Nov 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·J F TrapeJ Le Bras
Jul 10, 1998·Tropical Medicine & International Health : TM & IH·D ChandramohanR J Hayes
Sep 15, 1998·Tropical Medicine & International Health : TM & IH·V RobertD Fontenille
Oct 14, 1998·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·J F TrapeF Simondon
Aug 18, 1999·Archives of Disease in Childhood·L MuheM W Weber
Sep 2, 1999·Tropical Medicine & International Health : TM & IH·N White
Jun 27, 2001·The American Journal of Tropical Medicine and Hygiene·J F Trape
Feb 1, 2002·International Journal of Epidemiology·V DelaunayF Simondon
Dec 1, 2004·International Journal of Epidemiology·Jean-François EtardValérie Delaunay
Apr 4, 2006·Bulletin of the World Health Organization·Martin AdjuikFred Binka
Apr 12, 2006·Parasite : Journal De La Société Française De Parasitologie·N ValinA Garcia
Jan 11, 2007·Studies in Family Planning
Feb 28, 2008·Malaria Journal·Caterina GuinovartPedro L Alonso
Jun 14, 2008·Journal of Biosocial Science·Aurélien Franckel, Richard Lalou
Apr 28, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·A MunierJ P Chippaux
Mar 20, 2013·Revue D'épidémiologie Et De Santé Publique·A FayeA Tal-Dia

❮ Previous
Next ❯

Citations

Jul 20, 2010·The Lancet Infectious Diseases·Wendy Prudhomme O'MearaBrian Greenwood
Jan 29, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Aldiouma DialloJohn C Victor
Jul 26, 2021·Free Radical Biology & Medicine·Rafael Cardoso Maciel Costa SilvaMarcelo Torres Bozza

❮ Previous
Next ❯

Software Mentioned

dBase
Access
Stata
Excel

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.