Evolution of Neuroprosthetic Approaches to Restoration of Upper Extremity Function in Spinal Cord Injury

Topics in Spinal Cord Injury Rehabilitation
K L KilgoreP H Peckham

Abstract

Background: Spinal cord injury (SCI) occurring at the cervical levels can result in significantly impaired arm and hand function. People with cervical-level SCI desire improved use of their arms and hands, anticipating that regained function will result in improved independence and ultimately improved quality of life. Neuroprostheses provide the most promising method for significant gain in hand and arm function for persons with cervical-level SCI. Neuroprostheses utilize small electrical currents to activate peripheral motor nerves, resulting in controlled contraction of paralyzed muscles. Methods: A myoelectrically-controlled neuroprosthesis was evaluated in 15 arms in 13 individuals with cervical-level SCI. All individuals had motor level C5 or C6 tetraplegia. Results: This study demonstrates that an implanted neuroprosthesis utilizing myoelectric signal (MES)-controlled stimulation allows considerable flexibility in the control algorithms that can be utilized for a variety of arm and hand functions. Improved active range of motion, grip strength, and the ability to pick up and release objects were improved in all arms tested. Adverse events were few and were consistent with the experience with similar active implantable dev...Continue Reading

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References

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Citations

Jul 31, 2020·Neurological Research·Kevin L KilgoreP Hunter Peckham
May 21, 2020·Journal of Neuroengineering and Rehabilitation·Wafa TigraChristine Azevedo Coste
Feb 20, 2021·The Journal of Spinal Cord Medicine·Rosti ReadioffEdward K Chadwick
Dec 1, 2018·Bioelectronics in Medicine·Xiaoyu PengCristin G Welle

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