PMID: 8968015Dec 18, 1996Paper

Evolution of pregnancies and initial follow-up of newborns delivered after intracytoplasmic sperm injection

JAMA : the Journal of the American Medical Association
Gianpiero D PalermoZev Rosenwaks

Abstract

To analyze the in vivo development of embryos conceived after intracytoplasmic sperm injection (ICSI), as well as obstetric outcome, occurrence of chromosomal abnormalities, and rate of congenital malformations in neonates born as a result of this treatment. Retrospective study. University-based in vitro fertilization (IVF) clinic. A total of 751 couples in whom the male partners were presumed to be the cause of repeated failed IVF attempts or whose semen parameters were unacceptable for conventional IVF treatment. Analysis of pregnancies resulting from 987 ICSI cycles; pregnancy outcome data were obtained from the records of obstetrician-gynecologists and/or pediatricians. Pregnancy rates, obstetric outcome, and frequency of chromosomal abnormalities and congenital malformations. The overall clinical pregnancy (fetal heartbeat) rate was 44.3%, with a resultant delivery rate per ICSI cycle of 38.7% (n=382). In 8 of 11 miscarriages for which cytogenetic data were available, an autosomal trisomy was found, and 7 additional pregnancies were terminated because of a chromosomal abnormality after prenatal diagnosis. There was an equal distribution of vaginal vs cesarean deliveries (n=192 and n=190, respectively). Of the 578 neonates ...Continue Reading

Citations

Mar 30, 2007·Proceedings of the National Academy of Sciences of the United States of America·Zev Rosenwaks, Kristin Bendikson
Mar 1, 2002·Human Reproduction·Gianpiero D PalermoZev Rosenwaks
Mar 3, 2004·Obstetrics and Gynecology·Rebecca A JacksonMary S Croughan
Feb 12, 2005·Journal of Assisted Reproduction and Genetics·Alfred A RimmK Paul Katayama
Jul 22, 2010·European Journal of Human Genetics : EJHG·Michael S HildebrandRichard J H Smith
Aug 14, 2010·Obstetrics and Gynecology International·Yukiko KatagiriMineto Morita
Feb 21, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Sozos J Fasouliotis, Joseph G Schenker
Feb 4, 2006·Clinical Obstetrics and Gynecology·Queenie V NeriGianpiero D Palermo
Apr 8, 2006·Journal of Pediatric Orthopedics. Part B·Samer El HageFernand Dagher
Jun 10, 1998·Current Opinion in Obstetrics & Gynecology·G WrightS E Smith
Feb 15, 2002·Human Fertility : Journal of the British Fertility Society·Denny SakkasPatricia Grace Bianchi
Feb 15, 2002·Human Fertility : Journal of the British Fertility Society·Sarah Elliston
Jun 9, 2005·American Journal of Medical Genetics. Part a·Deborah A McDermottCraig T Basson
Aug 26, 1998·Lancet·A G SutcliffeB Lieberman
Apr 13, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kutluk OktayZev Rosenwaks
Nov 23, 2006·Revista Do Instituto De Medicina Tropical De São Paulo·Cynthia Liliane Motta do CantoJosé Eduardo Levi
May 14, 2007·Reproductive Medicine and Biology·Yukiko KatagiriMineto Morita
Jul 16, 2017·Reproduction : the Official Journal of the Society for the Study of Fertility·Nigel PereiraGianpiero D Palermo
Dec 2, 2014·PloS One·Gianpiero D PalermoZev Rosenwaks
Jun 27, 2002·Current Urology Reports·D M Nudell, L I Lipshultz
Feb 15, 2002·Human Fertility : Journal of the British Fertility Society·Ulla-Britt Wennerholm, Christina Bergh
May 13, 2014·Proceedings of the Japan Academy. Series B, Physical and Biological Sciences·Masakuni Suzuki

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