Evolution of serum biochemical indicators in anorexia nervosa patients: a 1-year follow-up study

Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association
E NovaA Marcos

Abstract

Long-term studies on the evolution of serum biochemical indicators in anorexia nervosa (AN) patients during treatment are lacking in the literature. Thus, a 1-year follow-up of serum biochemical parameters in a homogeneous group of AN patients was performed. Fourteen restricting-type AN patients were studied on admission to hospital, after 1 month of inpatient treatment and after 6 and 12 months after admission. Red blood cell count (RBC) and haemoglobin, serum glucose, total protein and the enzyme activities aspartate aminotransferase (AST), alkaline phosphatase (AlP), lactate dehydrogenase (LDH) and creatine kinase (CK) were significantly lower in patients on admission than in the control group. Total protein, high-density lipoprotein cholesterol (HDL-c), AST, AlP and CK showed significant changes among time points (anova, P < 0.05). Significant correlations were found between the change in RBC, haemoglobin, haematocrit, and the change in weight and body mass index (r = 0.74-0.86; P < 0.01). High cholesterol and amylase activity were found at all time points. While AST, LDH and CK reached control values within 6 months of treatment, AlP was always lower. Serum AlP, hypercholesterolaemia and RBC seem to need longer periods of ...Continue Reading

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Citations

Apr 23, 2011·Journal of Nutritional Science and Vitaminology·Ayana HasegawaMitsuru Higuchi
Dec 2, 2006·The Journal of Pediatrics·Madhusmita MisraAnne Klibanski
Mar 29, 2019·The International Journal of Eating Disorders·Alia A HussainJan M Sjögren
Aug 23, 2018·International Journal of Methods in Psychiatric Research·Montserrat GraellEsther Nova

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Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

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