PMID: 9541263Apr 16, 1998Paper

Evolution of the amelogenin gene in toothed and toothless vertebrates

European Journal of Oral Sciences
M Girondot, J Y Sire

Abstract

Amelogenin proteins constitute the major organic contents in forming enamel, but some previously published data indicate that the amelogenin gene could be present in several species lacking teeth or functional enamel. Therefore, amelogenin could have another, still unknown, function other than contributing to enamel formation. In order to test this hypothesis, the presence of this gene has been searched for in various vertebrates. We first compared the mammalian amelogenin sequences available in the literature to obtain the best chance of a successful detection of this gene in phylogenetically distant species. Using this analysis, we have shown that the occurrence of the amelogenin gene in the Y chromosome of primates and of an artiodactyl species is probably due to two independent duplications from genes on the X chromosome. Primers for PCR have therefore been synthesized and tested in eight species, five possessing teeth (human, two phylogenetically distant lizards, and two phylogenetically distant actinopterygians) and three lacking teeth (chicken and two phylogenetically distant turtles). The amelogenin gene has been detected in all species except those lacking teeth. This result indicates that the unique role of amelogenin...Continue Reading

Citations

Mar 14, 2003·Journal of Morphology·Sidney DelgadoJean-Yves Sire
May 6, 2006·European Journal of Oral Sciences·Jean-Yves SireMarc Girondot
Jan 8, 2013·Evolution; International Journal of Organic Evolution·Masayoshi TokitaJindawan Siruntawineti
Aug 12, 1999·Journal of Structural Biology·A G FinchamJ P Simmer
Sep 9, 2008·BMC Evolutionary Biology·Jean-Yves SireMarc Girondot
Jul 14, 2007·Cells, Tissues, Organs·Jean-Yves SireXun Gu
Dec 9, 1998·The Anatomical Record·M GirondotM Laurin
Feb 22, 2005·Archives of Oral Biology·Jean-Yves SireMarc Girondot
Jul 12, 2005·Calcified Tissue International·S K PrakashI B van den Veyver
Mar 27, 2007·Journal of Dental Research·S DelgadoJ-Y Sire
Feb 8, 2005·Journal of Molecular Evolution·Sidney DelgadoJean-Yves Sire
Nov 24, 2001·Molecular Biology and Evolution·S DelgadoM Girondot
Jul 27, 2001·Molecular Biology and Evolution·M IwaseN Takahata
Dec 10, 2020·International Journal of Molecular Sciences·Veronika VetyskovaJiri Vondrasek

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