PMID: 2124630Nov 1, 1990Paper

Evolution of the autosomal chorion cluster in Drosophila. IV. The Hawaiian Drosophila: rapid protein evolution and constancy in the rate of DNA divergence

Journal of Molecular Evolution
J C Martínez-Cruzado

Abstract

Autosomal chorion genes s18, s15, and s19 are shown to diverge at extremely rapid rates in closely related taxa of Hawaiian Drosophila. Their nucleotide divergence rates are at least as fast as those of intergenic regions that are known to evolve more extensively between distantly related species. Their amino acid divergence rates are the fastest known to date. There are two nucleotide replacement substitutions for every synonymous one. The molecular basis for observed length and substitution mutations is analyzed. Length mutations are strongly associated with direct repeats in general, and with tandem repeats in particular, whereas the rate for an average transition is twice that for an average transversion. The DNA sequence of the cluster was used to construct a phylogenetic tree for five taxa of the Hawaiian picture-winged species group of Drosophila. Assignment of observed base substitutions occurring in various branches of the tree reveals an excess of would-be homoplasies in a centrally localized 1.8-kb segment containing the s15 gene. This observation may be a reflection of ancestral excess polymorphisms in the segment. The chorion cluster appears to evolve at a constant rate regardless of whether the central 1.8-kb segm...Continue Reading

References

Nov 1, 1979·Journal of Molecular Evolution·N Kaplan, C H Langley
Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Jan 1, 1977·Annual Review of Biochemistry·A C WilsonT J White
May 1, 1989·Journal of Molecular Evolution·P M Sharp, W H Li
Nov 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·C SwimmerF C Kafatos
Jan 1, 1987·Journal of Molecular Evolution·T H Jukes
Jan 1, 1986·Journal of Molecular Evolution·E Zuckerkandl
Jan 1, 1986·Journal of Molecular Evolution·T H Jukes, V Bhushan
Jan 1, 1987·Journal of Molecular Evolution·W H LiP M Sharp
Jan 1, 1987·Journal of Molecular Evolution·R DeSalleA C Wilson
Jan 1, 1988·Journal of Molecular Evolution·A CacconeJ R Powell
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·R LecanidouF C Kafatos
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·R DeSalle, L V Giddings
Mar 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·C I Wu, W H Li
May 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·T H Eickbush, W D Burke
Jan 1, 1971·Journal of Molecular Evolution·R E Dickerson
May 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·H L CarsonH D Stalker
Jan 20, 1967·Science·W M Fitch, E Margoliash
Jan 1, 1982·Journal of Molecular Evolution·W M BrownA C Wilson
Jan 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·J R Powell
Jan 11, 1984·Nucleic Acids Research·R Staden
May 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·H Hayashida, T Miyata
Jul 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M D BigginG F Hong
Mar 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·N Takahata, M Slatkin
Jul 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·K IatrouF C Kafatos
Apr 1, 1980·Genetics·A R Templeton
Dec 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·T MiyataT Nishida
Oct 1, 1980·Cell·A EfstratiadisN J Proudfoot

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Citations

Aug 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M Kreitman
Apr 13, 2000·Annual Review of Entomology·M S CaterinoF A Sperling
Feb 26, 2004·Psychological Bulletin·Steven B RobbinsAaron Carlstrom

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