Evolution of the cichlid visual palette through ontogenetic subfunctionalization of the opsin gene arrays

Molecular Biology and Evolution
T C SpadyKaren L Carleton


The evolution of cone opsin genes is characterized by a dynamic process of gene birth and death through gene duplication and loss. However, the forces governing the retention and death of opsin genes are poorly understood. African cichlid fishes have a range of ecologies, differing in habitat and foraging style, which make them ideal for examining the selective forces acting on the opsin gene family. In this work, we present data on the riverine cichlid, Oreochromis niloticus, which is an ancestral outgroup to the cichlid adaptive radiations in the Great African lakes. We identify 7 cone opsin genes with several instances of gene duplication. We also characterize the spectral sensitivities of these genes through reconstitution of visual pigments. Peak absorbances demonstrate that each tilapia cone opsin gene codes for a spectrally distinct visual pigment: SWS1 (360 nm), SWS2b (423 nm), SWS2a (456 nm), Rh2b (472 nm), Rh2a beta (518 nm), Rh2a alpha (528 nm), and LWS (561 nm). Furthermore, quantitative reverse transcription polymerase chain reaction at 3 ontogenetic time points demonstrates that although only 4 genes (SWS2a, Rh2a alpha and beta, and LWS) are expressed in adults, mRNAs for the other genes are all expressed during o...Continue Reading


Feb 22, 1992·Proceedings. Biological Sciences·R E IbbotsonJ D Mollon
Dec 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·R Yokoyama, S Yokoyama
Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·D D OprianH G Khorana
Jan 1, 1980·Vision Research·R D Fernald, P A Liebman
Mar 1, 1995·Molecular Phylogenetics and Evolution·B S ChangD L Hartl
Sep 1, 1994·Journal of Molecular Evolution·E A RegisterS Yokoyama
Dec 1, 1994·Vision Research·O HisatomiF Tokunaga
Jan 12, 1993·Biochemistry·R L JohnsonK Nakanishi
Jul 11, 1996·Nature·G H JacobsJ Neitz
Dec 1, 1995·Molecular Phylogenetics and Evolution·T D KocherS F Lockwood
Aug 5, 2000·Science·K PalczewskiM Miyano
Oct 4, 2000·Visual Neuroscience·V I GovardovskiiK Donner
Nov 10, 2000·Science·M Lynch, J S Conery
Feb 13, 2001·Gene·S YokoyamaF B Radlwimmer
Jul 27, 2001·Molecular Biology and Evolution·K L Carleton, T D Kocher
Nov 24, 2001·Molecular Biology and Evolution·A D Briscoe
May 31, 2002·Brain Research. Developmental Brain Research·Johan ForsellPeter Ekström
Oct 5, 2002·Science·Catherine A HillLaurence J Zwiebel
Dec 10, 2002·Molecular Phylogenetics and Evolution·Masaki MiyaMutsumi Nishida
Mar 29, 2003·Journal of Molecular Evolution·Kenji SaitohMutsumi Nishida
May 21, 2003·Biochemistry·Yusuke Takahashi, Thomas G Ebrey
Nov 15, 2003·Current Biology : CB·Shaun P CollinAnn E O Trezise
Nov 25, 2003·Science·Michael Lynch, John S Conery
Dec 20, 2003·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·R C FullerJ Travis
May 25, 2004·Molecular Biology and Evolution·Johannes Spaethe, Adriana D Briscoe
Aug 6, 2004·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·David M HuntJames K Bowmaker
Aug 18, 2004·Trends in Genetics : TIG·Wei-Jen ChenAxel Meyer
Dec 17, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michelle M Mader, David A Cameron
Jan 15, 2005·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Toshifumi Minamoto, Isamu Shimizu
Mar 18, 2005·Molecular Biology and Evolution·Tyrone C SpadyKaren L Carleton
Apr 16, 2005·BMC Evolutionary Biology·Shruti Rastogi, David A Liberles
May 28, 2005·Nature Genetics·M Pilar Francino
Jun 7, 2005·Visual Neuroscience·Sven HalstenbergRussell D Fernald
Oct 11, 2005·Current Biology : CB·Ann E O Trezise, Shaun P Collin
Nov 30, 2005·Molecular Ecology·Karen L CarletonOle Seehausen

❮ Previous
Next ❯


Jun 5, 2010·Journal of Molecular Evolution·Adam R Smith, Karen L Carleton
Dec 21, 2010·Journal of Molecular Evolution·Corey T WatsonFelix Breden
Oct 20, 2012·Journal of Molecular Evolution·Christopher M HofmannKaren L Carleton
Mar 7, 2008·Visual Neuroscience·James K BowmakerGlen Jeffery
Mar 7, 2012·Visual Neuroscience·Timothy H Goldsmith
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Takashi TadaShozo Yokoyama
Jun 20, 2013·Proceedings of the National Academy of Sciences of the United States of America·Yoji NakamuraKiyoshi Inouye
Dec 1, 2009·Integrative and Comparative Biology·C Darrin Hulsey
Dec 1, 2009·Integrative and Comparative Biology·Christopher M Hofmann, Karen L Carleton
Sep 18, 2009·Molecular Biology and Evolution·Shozo Yokoyama, Takashi Tada
Jul 6, 2010·Molecular Biology and Evolution·Kelly E O'QuinKaren L Carleton
Oct 4, 2006·Proceedings. Biological Sciences·Margarete HoffmannChristine Dreyer
Oct 5, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·T W CroninP R Robinson
Oct 14, 2011·Genes, Brain, and Behavior·A R SmithK L Carleton
May 11, 2011·BMC Evolutionary Biology·Kelly E O'QuinKaren L Carleton
Dec 27, 2012·BMC Evolutionary Biology·Kelly E O'QuinKaren L Carleton
Oct 27, 2007·BMC Evolutionary Biology·Helena J BailesShaun P Collin
May 27, 2008·BMC Biology·Karen L CarletonEllis R Loew
Oct 30, 2010·BMC Biology·Shai SabbahCraig W Hawryshyn
Dec 31, 2014·Proceedings of the National Academy of Sciences of the United States of America·Fabio CortesiWalter Salzburger
Jan 13, 2015·Current Biology : CB·Timothy C Roth, Aaron R Krochmal
Oct 16, 2015·Molecular Biology and Evolution·Genevieve A C PhillipsN Justin Marshall
Jan 8, 2013·Zoology : Analysis of Complex Systems, ZACS·Caroline Marques Maia, Gilson Luiz Volpato
Nov 27, 2014·BMC Evolutionary Biology·Maarten HilbrantAlistair P McGregor
Apr 14, 2009·Trends in Genetics : TIG·Jun Gojobori, Hideki Innan
Aug 19, 2007·Brain Research·Barbara L Finlay
Aug 27, 2010·Journal of Fish Biology·O Puebla
Mar 1, 2009·Integrative Zoology·Karen Carleton
Nov 26, 2010·Molecular Ecology·Adam R SmithKaren L Carleton
Jun 2, 2012·Molecular Ecology·Wayne I L DaviesDavid M Hunt
Sep 30, 2010·The Journal of Comparative Neurology·W Ted AllisonPamela A Raymond
Mar 18, 2011·Evolution & Development·Kelly E O'QuinKaren L Carleton

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.