Evolution of the Fot1 transposons in the genus Fusarium: discontinuous distribution and epigenetic inactivation

Molecular Biology and Evolution
Marie-Josée DaboussiT Langin

Abstract

To understand the evolution of Fot1, a member of the pogo family widely dispersed in ascomycetes, we have performed a phylogenetic survey across the genus Fusarium divided into six sections. The taxonomic distribution of Fot1 is not homogeneous but patchy; it is prevalent in the Fusarium oxysporum complex, absent in closely related sections, and found in five species from the most distant section Martiella. Multiple copies of Fot1 were sequenced from each strain in which the element occurs. In three species, the Fot1 nucleotide sequence is 98% identical to that from F. oxysporum (Fox), whereas nucleotide divergence for host genes is markedly higher: 11% for partial nuclear 28S rDNA and up to 30% for the gene encoding nitrate reductase (nia). In two species, sequence divergence of Fot1-related elements relative to Fox ranged from 7% to 23% (16% average). Most of the sequence differences (82%) were C-to-T and G-to-A transitions. These mutations are distributed throughout the Fot1 sequences, although they tend to be concentrated in the middle portion of the elements. Analysis of the local sequence context of transitions revealed a hierarchy of site preferences. These characteristics are typical of the repeat-induced point mutation...Continue Reading

References

Mar 1, 1992·Molecular & General Genetics : MGG·M J DaboussiY Brygoo
Feb 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·M C KrickerM Radman
Jan 1, 1990·Annual Review of Genetics·E U Selker
Oct 1, 1989·Molecular and Cellular Biology·W S Grayburn, E U Selker
Jun 30, 1989·Science·E B CambareriE U Selker
Sep 1, 1989·Molecular & General Genetics : MGG·L Le ChevantonS Lebilcot
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·E U Selker, P W Garrett
Apr 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·R L MetzenbergE Morzycka-Wroblewska
Jul 8, 1994·Molecular & General Genetics : MGG·R S WilliamsB J Howlett
Mar 15, 1994·Experientia·J L Rossignol, G Faugeron
Dec 10, 1995·Molecular & General Genetics : MGG·D C GlayzerR P Oliver
Apr 15, 1996·Nucleic Acids Research·C NeuvegliseS Paris
Feb 20, 1996·Proceedings of the National Academy of Sciences of the United States of America·A F Smit, A D Riggs
Jun 6, 1998·Genes & Development·L Maloisel, J L Rossignol
Jul 2, 1998·Molecular & General Genetics : MGG·M BibbinsI F Connerton
Dec 5, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·F Kempken, U Kück
Jun 22, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·V Colot, J L Rossignol
Aug 4, 1999·Trends in Genetics : TIG·R H PlasterkZ Ivics
Jun 15, 2000·Current Genetics·A Hua-VanM J Daboussi
Jun 28, 2000·Proceedings of the National Academy of Sciences of the United States of America·K O'DonnellH H Casper
Aug 23, 2000·Molecular & General Genetics : MGG·A HamannH D Osiewacz
Mar 17, 2001·Molecular Microbiology·M G Li Destri NicosiaC Scazzocchio
Mar 30, 2001·Molecular Plant-microbe Interactions : MPMI·F VillalbaM C Grosjean-Cournoyer
May 22, 2001·Molecular Microbiology·F GraïaM Picard
Jul 19, 2001·Molecular Genetics and Genomics : MGG·Y ZhouJ A Kinsey
Sep 15, 2001·Molecular Biology and Evolution·A Hua-VanM J Daboussi
Mar 29, 2002·Molecular Genetics and Genomics : MGG·A Hua-VanM-J Daboussi

❮ Previous
Next ❯

Citations

Dec 5, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·F Kempken, U Kück
Nov 19, 2011·Journal of Molecular Evolution·Marie DufresneAurélie Hua-Van
Nov 10, 2009·Genetica·Louise J JohnsonMichael E Hood
Oct 9, 2007·Molecular Plant-microbe Interactions : MPMI·H Charlotte van der Does, Martijn Rep
Nov 28, 2007·Eukaryotic Cell·Rafael C Prados Rosales, Antonio Di Pietro
Dec 5, 2008·Microbiology and Molecular Biology Reviews : MMBR·Guy-Franck RichardBernard Dujon
Sep 1, 2009·Fungal Genetics and Biology : FG & B·Kerry O'DonnellBrice A J Sarver
Mar 15, 2006·Fungal Genetics and Biology : FG & B·Maria D MontielDavid B Archer
Feb 17, 2006·Fungal Genetics and Biology : FG & B·Yuichiro IidaTakashi Tsuge
Oct 7, 2003·Annual Review of Microbiology·Marie-Josée Daboussi, Pierre Capy
Jan 24, 2004·Molecular Biology and Evolution·Benjamin GorinsekDusan Kordis
Aug 12, 2005·Cytogenetic and Genome Research·B GorinsekD Kordis
Feb 10, 2018·Mobile DNA·Gabriel Luz WallauÉlgion Lúcio Silva Loreto
Sep 25, 2017·Microbiology Spectrum·John W TaylorPierre Gladieux
Sep 22, 2010·Fungal Genetics and Biology : FG & B·A John Clutterbuck

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.