Evolution of Wernicke-Korsakoff syndrome in self-neglecting alcoholics: preliminary results of relation with Wernicke-delirium and diabetes mellitus

The American Journal on Addictions
J W WijniaM Anne Goossensen

Abstract

We present a descriptive, retrospective study of initial symptoms, comorbidity, and alcohol withdrawal in 73 alcoholic patients with subsequent Korsakoff syndrome. In 25/73 (35%) of the patients the classic triad of Wernicke's encephalopathy with ocular symptoms, ataxia and confusion, was found. In at least 6/35 (17%) of the initial deliria (95% confidence interval: 10-25%) we observed no other underlying causes, thus excluding other somatic causes, medication, (recent) alcohol withdrawal, or intoxication. We suggest that these deliria may have been representing Wernicke's encephalopathy. A high frequency (15%) of diabetics may reflect a contributing factor of diabetes mellitus in the evolution of the Wernicke-Korsakoff syndrome.

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Citations

Dec 7, 2013·International Psychogeriatrics·Ineke J Gerridzen, M Anne Goossensen
Dec 27, 2019·Journal of Psychiatric and Mental Health Nursing·Mirjam Johanna van DamErik Oudman
May 22, 2020·Nursing Ethics·Ineke J GerridzenMarja F Depla
Mar 25, 2017·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Arantza SanvisensRoberto Muga
Nov 17, 2020·Alcoholism, Clinical and Experimental Research·Misha J OeyErik Oudman

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