Evolutionary dynamics of intron size, genome size, and physiological correlates in archosaurs

The American Naturalist
Eric Waltari, Scott V Edwards

Abstract

It has been proposed that intron and genome sizes in birds are reduced in comparison with mammals because of the metabolic demands of flight. To test this hypothesis, we examined the sizes of 14 introns in a nonflying relative of birds, the American alligator (Alligator mississippiensis), and in 19 flighted and flightless birds in 12 taxonomic orders. Our results indicate that a substantial fraction (66%) of the reduction in intron size as well as in genome size had already occurred in nonflying archosaurs. Using phylogenetically independent contrasts, we found that the proposed inverse correlation of genome size and basal metabolic rate (BMR) is significant among amniotes and archosaurs, whereas intron and genome size variation within birds showed no significant correlation with BMR. We show statistically that the distribution of genome sizes in birds and mammals is underdispersed compared with the Brownian motion model and consistent with strong stabilizing selection; that genome size differences between vertebrate clades are overdispersed and punctuational; and that evolution of BMR and avian intron size is consistent with Brownian motion. These results suggest that the contrast between genome size/BMR and intron size/BMR co...Continue Reading

References

Jan 1, 1985·Comparative Biochemistry and Physiology. A, Comparative Physiology·L Y Lewis, R E Gatten
Oct 5, 1995·Nature·A L Hughes, M K Hughes
Dec 1, 1993·Molecular Ecology·R W SladeP T Hale
Nov 28, 1996·Nature·D A PetrovD L Hartl
May 15, 1998·Nature·S Kumar, S B Hedges
Jun 18, 1998·Journal of Molecular Evolution·A HärlidU Arnason
Jun 6, 1998·Molecular Biology and Evolution·E N MoriyamaD L Hartl
Jul 21, 1998·Molecular Phylogenetics and Evolution·A E Feller, S B Hedges
Oct 10, 1998·Journal of Molecular Evolution·T A GorrT Kleinschmidt
Nov 25, 1998·Proceedings of the National Academy of Sciences of the United States of America·R Zardoya, A Meyer
Jun 25, 1999·Molecular Phylogenetics and Evolution·J G Groth, G F Barrowclough
Sep 4, 1999·Journal of Molecular Evolution·A E Vinogradov
Oct 12, 1999·Nature·A B Carvalho, A G Clark
Jun 17, 2000·Trends in Ecology & Evolution·E l Martins
Jul 25, 2000·Trends in Genetics : TIG·P Monaghan, N B Metcalfe
Nov 15, 2000·Genome Research·G K WongJ Yu
Mar 10, 2001·Nature·E S LanderUNKNOWN International Human Genome Sequencing Consortium
Apr 28, 2001·Biological Reviews of the Cambridge Philosophical Society·T R Gregory
Oct 20, 2001·Trends in Genetics : TIG·S Morand, R E Ricklefs
May 2, 2002·Proceedings of the National Academy of Sciences of the United States of America·Michael Lynch
Jun 6, 2002·Trends in Genetics : TIG·Alexander E Vinogradov
Jun 9, 1978·Science·S S CarlsonR D Maxson

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Citations

Feb 3, 2007·Immunogenetics·Alexander Iain TaylorRosaleen Ann Calvert
Jan 14, 2005·Chromosoma·Alexander E Vinogradov
Dec 28, 2011·Genome Biology and Evolution·Cheng SunRachel Lockridge Mueller
Aug 30, 2012·Genome Biology and Evolution·Qu Zhang, Scott V Edwards
Oct 1, 2008·Integrative and Comparative Biology·Daniel E JanesNicole Valenzuela
Oct 1, 2008·Integrative and Comparative Biology·Chris L OrganScott V Edwards
Jul 19, 2005·Proceedings. Biological Sciences·Scott V EdwardsAndrew M Shedlock
Mar 8, 2006·Proceedings. Biological Sciences·Alexander E Vinogradov, Olga V Anatskaya
Feb 20, 2007·Proceedings of the National Academy of Sciences of the United States of America·Andrew M ShedlockScott V Edwards
Jul 2, 2010·Annual Review of Genomics and Human Genetics·Daniel E JanesScott V Edwards
Jul 10, 2008·Molecular Phylogenetics and Evolution·Matthew E Gifford, Allan Larson
Mar 11, 2008·Zoology : Analysis of Complex Systems, ZACS·Rachel Lockridge MuellerJeffrey L Boore
Dec 23, 2004·Evolution; International Journal of Organic Evolution·Matthew G Fain, Peter Houde
Oct 25, 2007·Journal of Evolutionary Biology·I J LeitchM F Fay
Dec 18, 2008·Evolution; International Journal of Organic Evolution·June Y Lee, Scott V Edwards
Nov 9, 2004·Current Opinion in Genetics & Development·Alexander E Vinogradov
Sep 2, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Tyler A Elliott, T Ryan Gregory
Dec 27, 2012·Experimental Parasitology·Vaidas PalinauskasGediminas Valkiūnas
Jul 8, 2016·Ecology and Evolution·Rachel J SturgeKevin E Omland
Oct 8, 2011·Systematic Biology·June Y LeeScott V Edwards
Mar 28, 2018·Genes·Rafael KretschmerEdivaldo Herculano Correa de Oliveira
Dec 25, 2003·Molecular Biology and Evolution·Kevin P Johnson
Aug 13, 2004·Proceedings. Biological Sciences·Alexander E Vinogradov
Mar 9, 2007·Nature·Chris L OrganScott V Edwards
Jan 14, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Lucas J Legendre, Donald Davesne
Jan 14, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jacob D GardnerChris L Organ
Mar 10, 2007·Systematic Biology·Andrew M Shedlock
Jun 24, 2017·Systematic Biology·Scott V EdwardsAllan J Baker
Feb 4, 2021·Molecular Biology and Evolution·Baosheng WuKun Wang
Apr 11, 2021·Proceedings of the National Academy of Sciences of the United States of America·Sangeet LamichhaneyTariq Ezaz
Apr 30, 2021·Evolution; International Journal of Organic Evolution·Lucas J Legendre, Julia A Clarke

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