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Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

Genome Research

Feb 19, 2018

Jianghan QuAndrew Dac Smith

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Abstract

DNA methylation in the germline is among the most important factors influencing the evolution of mammalian genomes. Yet little is known about its evolutionary rate or the fraction of the methylome that has undergone change. We compared whole-genome, single-CpG DNA methylation profiles i...read more

Mentioned in this Paper

Species
Study of Epigenetics
Proximal
Cellular Component Organization
Operator gene
Whole Genome Amplification
Canis familiaris
Pan troglodytes
Genome
Gorilla <Western Gorilla>
21
2
45
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Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

Genome Research

Feb 19, 2018

Jianghan QuAndrew Dac Smith

PMID: 29259021

DOI: 10.1101/gr.225896.117

Abstract

DNA methylation in the germline is among the most important factors influencing the evolution of mammalian genomes. Yet little is known about its evolutionary rate or the fraction of the methylome that has undergone change. We compared whole-genome, single-CpG DNA methylation profiles i...read more

Mentioned in this Paper

Species
Study of Epigenetics
Proximal
Cellular Component Organization
Operator gene
21
2
45

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