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Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

Genome Research

Dec 21, 2017

Jianghan QuAndrew D Smith

Abstract

DNA methylation in the germline is among the most important factors influencing the evolution of mammalian genomes. Yet little is known about its evolutionary rate or the fraction of the methylome that has undergone change. We compared whole-genome, single-CpG DNA methylation profiles i...read more

Mentioned in this Paper

DNA Methylation [PE]
Genome
Genes
Regulation of Biological Process
Transcription Initiation Site
Transcription, Genetic
Sperm Cell
DNA Methylation
Operator gene
Gorilla <Eastern Gorilla>
21
2
45
Paper Details
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  • References96
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Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

Genome Research

Dec 21, 2017

Jianghan QuAndrew D Smith

PMID: 29259021

DOI: 10.1101/gr.225896.117

Abstract

DNA methylation in the germline is among the most important factors influencing the evolution of mammalian genomes. Yet little is known about its evolutionary rate or the fraction of the methylome that has undergone change. We compared whole-genome, single-CpG DNA methylation profiles i...read more

Mentioned in this Paper

DNA Methylation [PE]
Genome
Genes
Regulation of Biological Process
Transcription Initiation Site
Transcription, Genetic
Sperm Cell
DNA Methylation
Operator gene
Gorilla <Eastern Gorilla>
21
2
45

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Parasite Genetics

Parasite genetics is the study of the genetic material of parasites. Here is the latest research on parasite genetics.

Evolution of Gene Regulation (Keystone)

The evolution from single-celled to multicellular organisms required precise control of genes and gave cells the ability to be programmed for specific functions. Discover the latest research on the evolution of gene regulation and gene regulation in Drosophila in this feed.

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Paper Details
References
  • References96
  • Citations2
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