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Evolutionary forces shaping genomic islands of population differentiation in humans

BMC Genomics

Mar 24, 2012

Tamara HoferL Excoffier

Abstract

Levels of differentiation among populations depend both on demographic and selective factors: genetic drift and local adaptation increase population differentiation, which is eroded by gene flow and balancing selection. We describe here the genomic distribution and the properties of gen...read more

Mentioned in this Paper

Genetic Drift
In Silico
Genome
Recombination, Genetic
Biological Adaptation
Equilibrium
Erosion Lesion
Cell Differentiation Process
Genomics
Cytochrome P-450 CYP1A1
2
129
Paper Details
References
  • References84
  • Citations19
12345...
  • References84
  • Citations19
12

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Evolutionary forces shaping genomic islands of population differentiation in humans

BMC Genomics

Mar 24, 2012

Tamara HoferL Excoffier

PMID: 22439654

DOI: 10.1186/1471-2164-13-107

Abstract

Levels of differentiation among populations depend both on demographic and selective factors: genetic drift and local adaptation increase population differentiation, which is eroded by gene flow and balancing selection. We describe here the genomic distribution and the properties of gen...read more

Mentioned in this Paper

Genetic Drift
In Silico
Genome
Recombination, Genetic
Biological Adaptation
Equilibrium
Erosion Lesion
Cell Differentiation Process
Genomics
Cytochrome P-450 CYP1A1
2
129

Similar Papers Found In These Feeds

Perturb-seq

Perturb-seq has combined CRISPR gene inactivation and single-cell rna-sequencing (scRNA-seq) and is the newest addition to the geneticist's arsenal, providing scientists with study methods for functional genomics. Discover the latest research here.

Related Papers

Nature Genetics

Natural selection has driven population differentiation in modern humans

Nature GeneticsFebruary 5, 2008
Luis B BarreiroLluís Quintana-Murci
PLoS Genetics

The role of geography in human adaptation

PLoS GeneticsJune 9, 2009
Graham CoopJonathan Pritchard
Paper Details
References
  • References84
  • Citations19
12345...
  • References84
  • Citations19
12
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