Evolutionary pathway for the 2017 emergence of a novel highly pathogenic avian influenza A(H7N9) virus among domestic poultry in Tennessee, United States

Virology
Lei LiXiu-Feng Wan

Abstract

In March 2017, a novel highly pathogenic avian influenza A(H7N9) virus was detected at two commercial broiler breeder facilities in Tennessee, United States. In this study, a wild bird low pathogenic avian influenza A virus, A/blue-winged teal/Wyoming/AH0099021/2016(H7N9), was shown to be the probable precursor of the novel H7N9 virus; this low pathogenic virus has eight possible progenitor genes sharing > 99% sequence identity with the novel H7N9 virus. Phylogeographic analyses showed that viral gene constellations that formed and circulated among dabbling ducks contributed to the emergence of the novel H7N9 virus. This is in contrast to the virus that caused the 2016 H7N8 outbreak, which had more genetic contributions from viruses circulating among diving ducks. Study findings support the need for ongoing wild bird surveillance to monitor circulating viruses and to understand possible evolutionary pathways of virus emergence in poultry.

References

Mar 1, 1992·Microbiological Reviews·R G WebsterY Kawaoka
Jun 18, 2004·Emerging Infectious Diseases·David L SuarezDennis J Alexander
Jan 6, 2005·Vector Borne and Zoonotic Diseases·Scott KraussRobert G Webster
Apr 22, 2006·Science·Björn OlsenRon A M Fouchier
Oct 19, 2007·Journal of Virology·Yiming BaoDavid Lipman
Nov 13, 2007·BMC Evolutionary Biology·Alexei J Drummond, Andrew Rambaut
Sep 26, 2009·PLoS Computational Biology·Philippe LemeyMarc A Suchard
Feb 6, 2010·Science·Satoru IdeTakehiko Kobayashi
Mar 13, 2010·PloS One·Morgan N PriceAdam P Arkin
Oct 14, 2011·Viruses·Guan-Zhu Han, Michael Worobey
Jan 21, 2012·Influenza and Other Respiratory Viruses·R Burke SquiresRichard H Scheuermann
Jan 19, 2013·Molecular Biology and Evolution·Kazutaka Katoh, Daron M Standley

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts