Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)

Life
Kenji Ikehara

Abstract

It is no doubt quite difficult to solve the riddle of the origin of life. So, firstly, I would like to point out the kinds of obstacles there are in solving this riddle and how we should tackle these difficult problems, reviewing the studies that have been conducted so far. After that, I will propose that the consecutive evolutionary steps in a timeline can be rationally deduced by using a common event as a juncture, which is obtained by two counter-directional approaches: one is the bottom-up approach through which many researchers have studied the origin of life, and the other is the top-down approach, through which I established the [GADV]-protein world hypothesis or GADV hypothesis on the origin of life starting from a study on the formation of entirely new genes in extant microorganisms. Last, I will describe the probable evolutionary process from the formation of Earth to the emergence of life, which was deduced by using a common event-the establishment of the first genetic code encoding [GADV]-amino acids-as a juncture for the results obtained from the two approaches.

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Citations

Mar 1, 2020·Life·Martina PreinerJoana C Xavier
May 14, 2020·Mass Spectrometry Reviews·Alan McKenzie-CoeLisa M Jones
Aug 19, 2020·Viruses·Jonathan ColombetTélesphore Sime-Ngando
May 12, 2019·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Kenji Ikehara
Oct 15, 2019·Journal of Biomolecular Structure & Dynamics·J Dennis PollackDennis K Pearl
Jul 21, 2020·Chemical Reviews·Kamila B MuchowskaJoseph Moran
May 1, 2021·Life·Jozef Nahalka, Eva Hrabarova
May 19, 2021·Transcription·Lei Lei, Zachary Frome Burton

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