Evolutionary, structural and expression analysis of core genes involved in starch synthesis

Scientific Reports
Jianzhou QuDongwei Guo

Abstract

Starch is the main storage carbohydrate in plants and an important natural resource for food, feed and industrial raw materials. However, the details regarding the pathway for starch biosynthesis and the diversity of biosynthetic enzymes involved in this process are poorly understood. This study uses a comprehensive phylogenetic analysis of 74 sequenced plant genomes to revisit the evolutionary history of the genes encoding ADP-glucose pyrophosphorylase (AGPase), starch synthase (SS), starch branching enzyme (SBE) and starch de-branching enzyme (DBE). Additionally, the protein structures and expression patterns of these four core genes in starch biosynthesis were studied to determine their functional differences. The results showed that AGPase, SS, SBE and DBE have undergone complicated evolutionary processes in plants and that gene/genome duplications are responsible for the observed differences in isoform numbers. A structure analysis of these proteins suggested that the deletion/mutation of amino acids in some active sites resulted in not only structural variation but also sub-functionalization or neo-functionalization. Expression profiling indicated that AGPase-, SS-, SBE- and DBE-encoding genes exhibit spatio-temporally di...Continue Reading

References

Oct 1, 1993·The Plant Cell·M A Lopes, B A Larkins
Jan 6, 2000·Archives of Biochemistry and Biophysics·H CaoA M Myers
May 16, 2000·Nature·D MoreiraH Philippe
Feb 22, 2001·Genome Biology·J RossD J Bowles
May 5, 2001·Annual Review of Plant Physiology and Plant Molecular Biology·Odd-Arne Olsen
Sep 25, 2003·Annual Review of Plant Biology·Steven G Ball, Matthew K Morell
Mar 11, 2004·The Plant Cell·Odd-Arne Olsen
May 4, 2004·Plant Physiology·Joanna M CrossL Curtis Hannah
Feb 5, 2005·The EMBO Journal·Xiangshu JinJames H Geiger
Oct 18, 2005·Photosynthesis Research·Miguel A BallicoraJack Preiss
Oct 27, 2005·The Journal of Eukaryotic Microbiology·Sina M AdlMax F J R Taylor
Jan 31, 2006·Plant Physiology·Naoko FujitaYasunori Nakamura
May 3, 2006·Journal of Molecular Biology·Bunzo MikamiYoshio Katsuya
Sep 11, 2007·Bioscience, Biotechnology, and Biochemistry·Yoshinori TakashimaHirokazu Matsui
Sep 12, 2007·Bioinformatics·M A LarkinD G Higgins
Dec 21, 2007·Molecular Biology and Evolution·Philippe DeschampsSteven Ball
Oct 1, 2008·Trends in Plant Science·Philippe DeschampsSteven G Ball
Mar 3, 2010·Annual Review of Plant Biology·Samuel C ZeemanAlison M Smith
Jan 1, 2009·International Journal of Plant Genomics·Boryana S StamovaDiane M Beckles
Apr 20, 2010·Plant Physiology and Biochemistry : PPB·Jong-Seong JeonYasunori Nakamura
Sep 25, 2010·Journal of Molecular Biology·Malene Bech Vester-ChristensenAnette Henriksen
Oct 15, 2010·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Alex BatemanRobert D Finn

❮ Previous
Next ❯

Citations

Sep 10, 2020·Plants·Yong-Gu Cho, Kwon-Kyoo Kang
Jan 27, 2019·International Journal of Molecular Sciences·Kangyong ZhaLongjiang Gu
Aug 18, 2020·Plant Signaling & Behavior·Hong-Di ShiDan-Dan Liu
Oct 7, 2020·Proceedings of the National Academy of Sciences of the United States of America·Can BaysalPaul Christou
Mar 2, 2021·Journal of Agricultural and Food Chemistry·Yuyue ZhongDongwei Guo
May 20, 2020·Current Opinion in Plant Biology·Melanie R Abt, Samuel C Zeeman
Apr 30, 2021·Biomacromolecules·Jihui ZhuQiaoquan Liu
Jun 3, 2021·International Journal of Molecular Sciences·Tosin Victor AdegokeJian Zhang
Jun 3, 2021·Plants·Karine E Janner de FreitasAntonio Costa de Oliveira
Nov 27, 2020·Biotechnology Advances·Rujia ChenZefeng Yang
Jun 1, 2021·Genome Génome / Conseil National De Recherches Canada·Xiaojuan ZhongQiantao Jiang
Aug 28, 2021·International Journal of Molecular Sciences·Bianyun YuDengjin Bing
Sep 14, 2021·Frontiers in Plant Science·Rahele PanahabadiNaser Farrokhi

❮ Previous
Next ❯

Datasets Mentioned

BETA
PRJNA299361
SRP037559

Methods Mentioned

BETA
ISAs
RNA-seq
PCR

Software Mentioned

Cytoscape
PhyML
R
BLASTp
iTOL
string
HMMER3
PyMOL
MEGA
ClustalW

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.