PMID: 9547447Apr 21, 1998Paper

Evolving concepts of heart failure: cooling furnace, malfunctioning pump, enlarging muscle--Part I

Journal of Cardiac Failure
A M Katz

Abstract

Understanding of the causes of dyspnea and anasarca, the cardinal features of heart failure, has changed dramatically since Greco-Roman times, when sputum and pleural effusions were thought to originate in the brain, and the heart was believed to heat and distribute the vital spirit. It was not until the seventeenth century, when Harvey demonstrated that the heart was a pump and autopsy descriptions revealed valve abnormalities that interfered with the circulation, that it became possible to identify the role of heart disease in causing shortness of breath and edema. Morgagni's recognition, toward the end of the eighteenth century, that overload caused the heart to enlarge was followed less than 50 years later by Corvisart's distinction between hypertrophy and dilation. Differences in the architecture of failing hearts focused attention of nineteenth-century clinical scientists on the myocardial response to overload, and by the end of this century overload-induced hypertrophy was recognized not only to have immediate adaptive effects, but also to cause progressive degeneration of the heart muscle. This focus on the failing myocardium ended in the early years of the twentieth century, when new discoveries in hemodynamic physiolo...Continue Reading

Citations

Aug 7, 2002·International Journal of Cardiology·Wolfram Doehner, Stefan D Anker
Jan 12, 2001·Journal of the American College of Cardiology·L W StevensonA Wichman
Feb 13, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·L W Stevenson, R L Kormos
Sep 9, 2000·Progress in Pediatric Cardiology·M Auslender
May 28, 2003·Journal of Cellular and Molecular Medicine·A M Katz
Apr 2, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·Arnold M Katz
Oct 17, 2001·Current Cardiology Reports·P A Poole-Wilson
Dec 11, 2002·Expert Opinion on Therapeutic Targets·Volker RoenickeThomas Henkel
May 19, 2012·International Journal of Cardiology·Kazem KhodadoustGarabed Eknoyan
Aug 17, 2006·Journal of Cardiac Failure·Magdi M SabaMandeep R Mehra
Jun 13, 2006·Palliative Medicine·M J Johnson, T Houghton
Jun 2, 2004·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Tibor Kempf, Kai C Wollert
Oct 8, 2009·Circulation. Heart Failure·Daphne T Hsu, Gail D Pearson
Nov 5, 2005·Journal of Advanced Nursing·de Sales Turner
Apr 12, 2001·The Journal of the Association of Nurses in AIDS Care : JANAC·J KylmäJ Lähdevirta
Jun 8, 2017·Heart Failure Reviews·Abesh Bera, Dwaipayan Sen
Dec 16, 2010·Journal of Molecular and Cellular Cardiology·Nicky M BoontjeJolanda van der Velden

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