Evolving Concepts of Pulmonary Hypertension Secondary to Left Heart Disease

Current Heart Failure Reports
Bhavadharini Ramu, Thenappan Thenappan

Abstract

Pulmonary hypertension associated with left heart disease is the most common form of pulmonary hypertension. Although its pathophysiology remains incompletely understood, it is now well recognized that the presence of pulmonary hypertension is associated with a worse prognosis. Right ventricular failure has independent and additive prognostic value over pulmonary hypertension for adverse outcomes in left heart disease. Recently, several new terminologies have been introduced to better define and characterize the nature and severity of pulmonary hypertension. Several new treatment options including the use of pulmonary arterial hypertension specific therapies are being considered, but there is lack of evidence. Here, we review the recent advances in this field and summarize the diagnostic and therapeutic modalities of use in the management of pulmonary hypertension associated with left heart disease.

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Citations

Jul 23, 2016·Journal of the American College of Cardiology·Ori Ben-Yehuda, Lewis J Rubin
Feb 16, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Jennifer L PhilipNaomi C Chesler
Oct 6, 2017·Journal of the Intensive Care Society·Ignacio de Asua, Alex Rosenberg
Jan 18, 2022·Biomechanics and Modeling in Mechanobiology·Michelle A BartoloMette S Olufsen

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