PMID: 9166395Jan 1, 1997Paper

Ex vivo estimation of thoracolumbar vertebral body compressive strength: the relative contributions of bone densitometry and vertebral morphometry

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
S EdmondstonP Breidahl

Abstract

The estimation of vertebral fracture risk in individuals with suspected osteopenia is commonly based on measurements of lumbar spine bone density. The efficacy of vertebral size and deformity, as assessed by vertebral morphometry, in the prediction of fractures has been less studied. In an ex vivo investigation the regional relationships between vertebral size, vertebral deformity, bone density and compressive strength throughout the thoracolumbar spine were examined. In 16 vertebral columns (T1-L5) the bone mineral content (BMC) and bone mineral density (BMD) of each segment were measured using lateral projection dual-energy X-ray absorptiometry, and the vertebral cancellous density (VCD) and mid-vertebral cross-sectional area (CSA) measured using quantitative computed tomography. Vertebral body heights were determined from mid-sagittal CT scans, and vertical height ratios calculated for each segment. The failure load and failure stress of the isolated vertebral bodies were determined using a material testing device. Separate analyses were performed for the upper (T1-4), middle (T5-8) and lower (T9-12) thoracic, and lumbar (L1-5) segments. In all regions, failure load was strongly correlated with BMD (r = 0.82-0.86), moderatel...Continue Reading

References

Jan 1, 1992·Calcified Tissue International·M Kleerekoper, D A Nelson
Jun 1, 1991·Annals of Internal Medicine·P D RossR D Wasnich
Apr 1, 1989·Calcified Tissue International·S A ErikssonJ U Lindgren
May 1, 1995·The Journal of Clinical Investigation·V GilsanzE E Schulz
May 1, 1993·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P D RossR D Wasnich
Dec 1, 1995·Calcified Tissue International·D DiacintiG F Mazzuoli

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Citations

Mar 7, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A Ruyssen-WitrandC Roux
Apr 4, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA· PrakashS Madhyastha
Dec 24, 2004·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Meena M SranThomas R Oxland
Jul 4, 2006·Journal of Bone and Mineral Metabolism·Xiang-Ding ChenHong-Wen Deng
Aug 27, 2009·Annals of Biomedical Engineering·Emily S NelsonJerry G Myers
Jan 30, 2004·The Spine Journal : Official Journal of the North American Spine Society·Mark M KayanjaIsador H Lieberman
Jan 8, 2000·Clinical Biomechanics·M M PanjabiJ Cholewicki
Mar 7, 2000·Spine·D E ShepherdD W Hukins
Sep 22, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Y DuanE Seeman
Jan 10, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·E SeemanJ Edmonds
Aug 9, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D E AndersonM L Bouxsein
Jul 5, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Andrew M BriggsKim L Bennell
Sep 29, 2009·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Ahad ZeinaliShahram Akhlaghpoor
Apr 15, 2009·The Spine Journal : Official Journal of the North American Spine Society·Jenni M BuckleyChristopher Ames
Oct 20, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Hui ShenHong-Wen Deng
Oct 18, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Tony M KeavenyJavier A San Martin
May 5, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Blaine A ChristiansenMary L Bouxsein
Jan 18, 2005·The Spine Journal : Official Journal of the North American Spine Society·Ioannis N GaitanisAvinash G Patwardhan
Aug 9, 2016·Journal of Biomechanical Engineering·Valentina DanesiLuca Cristofolini
Jan 17, 2004·Journal of Human Genetics·Wei-Xia JianHong-Wen Deng
Dec 8, 2016·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Pan YangGuo-Gang Sun
Aug 15, 2021·Journal of Orthopaedic Surgery and Research·Jacob T LandeckColin D White

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