Ex vivo liver resection and autotransplantation with cardiopulmonary bypass for hepatoblastoma in children: A case report

Pediatric Transplantation
Shu-Jun ShiQuan Kang

Abstract

Some primary and secondary liver carcinomas cannot be resected using a conventional approach due to their size, location, or major vascular invasion. The aim of this study was to explore the application of ex vivo liver resection and autotransplantation for complicated HB in children. A 1.5-year-old girl with HB after repeated chemotherapy was analyzed. In this patient, tumor invasion includes the IV, V, and VIII liver segments, and thrombosis formed in the inferior vena cava and right atrium. It is difficult to obtain complete tumor resection using conventional hepatectomy. The patient was treated via ex vivo liver resection and autotransplantation, and tumor thrombus in the inferior vena cava and right atrium was removed via cardiopulmonary bypass. Operative methods and precautions were analyzed during and after the operation. The operation was completed successfully within 8 hours, and the liver's cold ischemia time was 190 minutes. The patient recuperated successfully, and the liver's function and AFP levels gradually tended to normalize 2 weeks after the operation. Ultrasonic examination revealed that the blood flow velocity of the hepatic vein, portal vein, and hepatic artery was good. The patient recovered and was discha...Continue Reading

References

May 20, 2000·Surgery·K J OldhaferR Pichlmayr
Sep 16, 2000·Journal of the American College of Surgeons·J R MadariagaS Iwatsuki
Apr 15, 2004·Annals of Surgery·Alan W HemmingRichard J Howard
Dec 23, 2006·Pediatric Radiology·Derek J RoebuckUNKNOWN International Childrhood Liver Tumor Strategy Group
Jan 17, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Rudolf MaibachGiorgio Perilongo
Mar 13, 2014·Journal of Pediatric Hematology/oncology·Angela D Trobaugh-LotrarioJames H Feusner
Mar 31, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Meredith A BakerCataldo Doria
Dec 14, 2016·Seminars in Pediatric Surgery·Daniel C Aronson, Rebecka L Meyers
Dec 21, 2016·Liver Cancer·Yoshikuni KawaguchiNorihiro Kokudo
Jun 12, 2017·Radiologic Clinics of North America·Ali YikilmazEdward Y Lee

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