Ex-vivo recruitment and x-ray assessment of donor lungs in a challenging retrieval from a donor supported by lvad using the portable normothermic perfusion system: a case report

Journal of Cardiothoracic Surgery
Marco SchiavonFederico Rea

Abstract

Lung transplantation (LTx) is limited by the shortage of suitable donors. To overcome this problem, many programs have begun to use donors with extended criteria (marginal donors). However, brain-dead patients with implanted mechanical circulatory support system have rarely been considered as potential lung donors. This case demonstrates the feasibility of lung transplantations from organ donors supported by a mechanical circulatory support system despite the possible difficulties of lung retrieval. Our case presents a successful procurement and bilateral lung transplantation from a donor supported by a left ventricular assist device (LVAD) who experienced an intraoperatively haemodynamic complication. The use of portable normothermic perfusion device let us to reduce ischemic injury and assess these marginal donor lungs helping us to determine the clinical suitability for transplantation. Given our extensive experience with the device instrumentation and management, the EVLP process was uneventful with excellent post-transplant course. This case report demonstrates the feasibility of lung transplantations from organ donors supported by a mechanical circulatory support system using the portable normothermic perfusion platform t...Continue Reading

References

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Citations

May 17, 2018·The New England Journal of Medicine·Stefan G Tullius, Hamid Rabb
Oct 24, 2018·Transplant International : Official Journal of the European Society for Organ Transplantation·Marco SchiavonRea Federico
Oct 16, 2021·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Antonio LoforteDavide Pacini

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Methods Mentioned

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X-ray
biopsy
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OCS

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