PMID: 2106958Feb 3, 1990Paper

Examination of fetuses after induced abortion for fetal abnormality

BMJ : British Medical Journal
J Clayton-SmithD Donnai

Abstract

To determine the accuracy of midtrimester diagnosis of fetal abnormality by examination and investigation of fetuses after induced abortion. Prospective study over five years of fetuses aborted in the midtrimester because of abnormalities detected by ultrasonography and amniocentesis. Techniques included a full external examination by a clinical geneticist with experience in dysmorphology and other investigations including necropsy. Regional genetic centre. Clinicians working within the North Western region who wished to use the service offered. 133 Fetuses were aborted because of abnormalities detected on ultrasonography and 115 because of abnormal findings on amniotic fluid analysis. In a further two cases fetal abnormality was diagnosed by molecular genetic and biochemical techniques. Among the fetuses with abnormal scans the pretermination diagnosis was changed or refined in a way which affected genetic counselling in 53 of 133 cases. Among the 115 fetuses diagnosed as abnormal by amniocentesis the pretermination diagnosis was confirmed in 112 cases and altered in three. Fetuses aborted because of abnormalities detected by screening should be examined by suitably experienced clinicians, both for accurate genetic counselling...Continue Reading

References

Jun 1, 1988·International Journal of Sports Medicine·S L LindstedtH A Thronson
Sep 1, 1987·Baillière's Clinical Obstetrics and Gynaecology·D Donnai

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Citations

Nov 27, 1999·Obstetrics and Gynecology·O M Faye-PetersenK D Wenstrom
May 17, 2000·Current Opinion in Obstetrics & Gynecology·D Chitayat, R Babul-Hirji
Nov 1, 1995·Journal of Clinical Pathology·G M VujanićA J Dawson
Mar 5, 2013·Archives of Pathology & Laboratory Medicine·Linda M ErnstMichael K Fritsch
Nov 24, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A KaasenG Haugen
Jan 7, 2011·Prenatal Diagnosis·Lyn S Chitty, Tze Kin Lau
Nov 30, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Laura HauerbergLisa Leth Maroun
Apr 1, 1992·Pathology·H M Chambers
Oct 2, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C StruksnaesC Vogt
Jun 10, 2000·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C V IsaksenS H Torp
Aug 19, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C VotinoJ Jani
Mar 16, 2017·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M ShruthiM Kabra
May 1, 1994·British Journal of Obstetrics and Gynaecology·I R BrandR J Lilford
Jul 1, 1991·British Journal of Obstetrics and Gynaecology·D I Rushton
Mar 24, 1998·Prenatal Diagnosis·L S Chitty, P P Pandya
Aug 31, 2002·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Sanne J GordijnT Yee Khong
Sep 24, 2004·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Mirlene C S P CernachDecio Brunoni
Oct 21, 2016·Archives of Pathology & Laboratory Medicine·Carolin A BoeckingWalter E Finkbeiner
Jul 1, 1993·Journal of Clinical Ultrasound : JCU·M J WestonP J Berry
May 15, 2002·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Lami YeoAnthony M Vintzileos
Oct 22, 2009·Fetal and Pediatric Pathology·Robert Roger LebelJulianne S Collins
Feb 9, 1999·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·C C SunJ S Dungan

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