Abstract
Parabens and sorbic acid are commonly used as food preservatives due to their antimicrobial effect. However, their use in foods for infants and young children is not permitted in the European Union. Previous studies found these compounds in some gel-filled baby teethers, whereby parabens, which are well-known as endocrine disruptors, were identified in the polymer-based chewing surface consisting of ethylene-vinyl acetate (EVA). To assess the exposure of infants and young children to these products, the application of parabens in teethers should be thoroughly investigated. Therefore, the present study aimed to apply a representative migration test procedure combined with an accurate analytical method to examine gel-filled baby teethers without elaborate sample preparation, high costs, and long processing times. Accordingly, solid-phase extraction (SPE), in combination with a stable isotope dilution assay (SIDA) and subsequent gas chromatography-mass spectrometry (GC-MS) for analysis of methyl-, ethyl-, and n-propylparaben (MeP, EtP, and n-PrP), was found to be well-suited, with recoveries ranging from 93 to 99%. The study compared the release of these parabens from intact teether surfaces into water and saliva simulant under re...Continue Reading
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Citations
Nov 21, 2019·Journal of Separation Science·Yiqian GaoChuan-Fan Ding
Jul 1, 2021·Journal of Exposure Science & Environmental Epidemiology·Nicolò AurisanoOlivier Jolliet
Jul 23, 2021·Food Chemistry·Paula VeraJeff Goshawk
Aug 23, 2021·Ecotoxicology and Environmental Safety·Yahui LiuQing Lv