Examining phylogenetic relationships among gibbon genera using whole genome sequence data using an approximate bayesian computation approach

Genetics
Krishna R VeeramahMichael F Hammer

Abstract

Gibbons are believed to have diverged from the larger great apes ∼16.8 MYA and today reside in the rainforests of Southeast Asia. Based on their diploid chromosome number, the family Hylobatidae is divided into four genera, Nomascus, Symphalangus, Hoolock, and Hylobates. Genetic studies attempting to elucidate the phylogenetic relationships among gibbons using karyotypes, mitochondrial DNA (mtDNA), the Y chromosome, and short autosomal sequences have been inconclusive . To examine the relationships among gibbon genera in more depth, we performed second-generation whole genome sequencing (WGS) to a mean of ∼15× coverage in two individuals from each genus. We developed a coalescent-based approximate Bayesian computation (ABC) method incorporating a model of sequencing error generated by high coverage exome validation to infer the branching order, divergence times, and effective population sizes of gibbon taxa. Although Hoolock and Symphalangus are likely sister taxa, we could not confidently resolve a single bifurcating tree despite the large amount of data analyzed. Instead, our results support the hypothesis that all four gibbon genera diverged at approximately the same time. Assuming an autosomal mutation rate of 1 × 10(-9)/si...Continue Reading

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Citations

Jul 1, 2017·Molecular Ecology·Megan L SmithBryan C Carstens
Aug 23, 2018·Evolutionary Anthropology·Julia M Zichello
Sep 13, 2019·Molecular Ecology Resources·Chris C R Smith, Samuel M Flaxman
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Jul 23, 2020·American Journal of Primatology·M Kathleen PitirriDavid R Begun
Nov 17, 2020·Annual Review of Animal Biosciences·Joseph D OrkinTomas Marques-Bonet

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