Examining the effectiveness of antipsychotic medication in first-episode psychosis

Journal of Psychopharmacology
Mark TaylorJari Tiihonen

Abstract

The regular use of antipsychotic medication is known to improve overall outcomes and diminish risk of relapse, but applying the results of randomised controlled trials (RCTs) into routine clinical practice is not always straightforward. Furthermore, psychiatrists, service users and policy makers can have trouble keeping up with the burgeoning and, at times, conflicting results from research trials, meta-analysis and systematic reviews. In this paper we examine the differences between efficacy and effectiveness trials with regard to antipsychotic medication with a focus on first-episode psychosis, after reviewing the relative contribution of antipsychotic medication to outcomes in schizophrenia.

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Citations

Feb 26, 2016·Translational Psychiatry·J M StevensonJ R Bishop
Sep 26, 2015·Early Intervention in Psychiatry·Georgia L StevensJacqueline Zummo
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May 18, 2012·Journal of Psychopharmacology·Mark TaylorBrian Leonard
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Aug 18, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·Mario LucianoAndrea Fiorillo

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Methods Mentioned

BETA
SGA

Software Mentioned

CATIE
EUFEST
CUtLASS

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Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here