Examining the relationship between sepsis and oropharyngeal dysphagia in hospitalised elderly patients: a retrospective cohort study

Frontline Gastroenterology
Ayodele SasegbonShaheen Hamdy

Abstract

Elderly people are recognised to be at increased risk of oropharyngeal dysphagia (OPD), the causes of which are multifactorial. Our aim was to identify if sepsis is associated with OPD in the elderly during hospitalisation in the absence of known other risk factors for OPD. A hospital electronic database was searched for elderly patients (≥65 years) referred for assessment for suspected dysphagia between March 2013 and 2014. Exclusion criteria were age <65 years, pre-existing OPD or acute OPD secondary to acute intracranial event, space-occupying lesion or trauma. Data were collected on factors including age, sex, comorbidities, existing OPD, sepsis, microbiology, recovery of OPD and medication. Sepsis was defined as evidence of a systemic inflammatory response syndrome with a clinical suspicion of infection. A total of 301 of 1761 screened patients referred for dysphagia assessment met the inclusion criteria. The prevalence of sepsis and subsequent OPD was 16% (51/301). The mean age was 83 years (median 81 years). The most common comorbidity was dementia (31%). The majority (84%) failed to recover swallowing during their hospital stay, 12% had complications of aspiration and 35% died. The most common source of sepsis was from ...Continue Reading

References

Sep 1, 1995·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·J RobbinsE Luschei
Jan 1, 1994·Dysphagia·K V Kuhlemeier
Jan 1, 1994·Dysphagia·S Jaradeh
Mar 22, 2002·Intensive Care Medicine·Corinne AlbertiRoger Le Gall
Mar 29, 2003·Intensive Care Medicine·Mitchell M LevyUNKNOWN International Sepsis Definitions Conference
Apr 5, 2003·Stroke; a Journal of Cerebral Circulation·Deborah J C RamseyLalit Kalra
Dec 20, 2005·Dysphagia·Deborah RamseyLalit Kalra
Oct 21, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Hae-young KimLauren L Patton
Mar 5, 2008·Alimentary Pharmacology & Therapeutics·G D Eslick, N J Talley
Jun 2, 2009·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Denise M NeyJoAnne Robbins
Nov 9, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Lydia CvejicPaul Guy
Apr 28, 2012·Dysphagia·Fumiyo TamuraKen Yaegaki
May 31, 2013·Annals of Intensive Care·Romain SonnevilleTarek Sharshar
Jun 28, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Joerg ZielskeOrlando Guntinas-Lichius
Apr 9, 2015·Journal of Clinical Gastroenterology·Juan-R MalageladaAnton Le Mair
May 27, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A Sasegbon, S Hamdy

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Citations

Sep 23, 2020·American Journal of Speech-language Pathology·José VergaraLucia Figueiredo Mourão
Apr 19, 2020·American Journal of Physical Medicine & Rehabilitation·Martin B BrodskyMarlís González-Fernández

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