Examining the Reproducibility of 6 Published Studies in Public Health Services and Systems Research

Journal of Public Health Management and Practice : JPHMP
Jenine K HarrisJonathon P Leider

Abstract

Research replication, or repeating a study de novo, is the scientific standard for building evidence and identifying spurious results. While replication is ideal, it is often expensive and time consuming. Reproducibility, or reanalysis of data to verify published findings, is one proposed minimum alternative standard. While a lack of research reproducibility has been identified as a serious and prevalent problem in biomedical research and a few other fields, little work has been done to examine the reproducibility of public health research. We examined reproducibility in 6 studies from the public health services and systems research subfield of public health research. Following the methods described in each of the 6 papers, we computed the descriptive and inferential statistics for each study. We compared our results with the original study results and examined the percentage differences in descriptive statistics and differences in effect size, significance, and precision of inferential statistics. All project work was completed in 2017. We found consistency between original and reproduced results for each paper in at least 1 of the 4 areas examined. However, we also found some inconsistency. We identified incorrect transcripti...Continue Reading

References

Jun 1, 2004·BMC Medical Research Methodology·Emili García-Berthou, Carles Alcaraz
Jul 16, 2004·Journal of Public Health Management and Practice : JPHMP·Glen P MaysF Douglas Scutchfield
Mar 3, 2006·American Journal of Epidemiology·Roger D PengScott L Zeger
Sep 6, 2011·Nature Reviews. Drug Discovery·Florian PrinzKhusru Asadullah
Dec 7, 2011·Science·Roger D Peng
Mar 31, 2012·Nature·C Glenn Begley, Lee M Ellis
Apr 25, 2012·American Journal of Preventive Medicine·Jenine K HarrisGlen P Mays
Aug 18, 2012·American Journal of Preventive Medicine·Ross C BrownsonPaul C Erwin
Oct 3, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ferric C FangArturo Casadevall
Jan 15, 2014·Lancet·John P A IoannidisRobert Tibshirani
Feb 14, 2014·Nature·Regina Nuzzo
Oct 22, 2014·PLoS Medicine·John P A Ioannidis
Sep 1, 2015·Science·UNKNOWN Open Science Collaboration
Oct 27, 2015·Behavior Research Methods·Michèle B NuijtenJelte M Wicherts
Mar 5, 2016·Science·Colin F CamererHang Wu
Mar 5, 2016·Science·Christopher J AndersonKellylynn Zuni
Feb 22, 2017·American Journal of Preventive Medicine·Rebekah R JacobRoss C Brownson
Aug 16, 2017·Nature Ecology & Evolution·Julia S Stewart LowndesBenjamin S Halpern

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