Excellent reliability of nurse-based bedside diagnosis of acute myocardial infarction by rapid dry-strip creatine kinase MB, myoglobin, and troponin T

American Heart Journal
C SylvénG Rasmanis

Abstract

With the aim to compare the diagnostic efficacy as regards acute myocardial infarction of two rapid dry-strip tests, one with both creatine kinase MB (CK-MB) and myoglobin (C + M) and the other with troponin T, and to test the reliability of bedside diagnosis by the coronary care unit (CCU) nurse, 151 patients with acute chest pain admitted to the CCU were investigated. There was no difference in diagnostic performance between rapid tests and quantitative determinations. With <6-hour duration of symptoms, the sensitivity was better for C + M than for troponin T (72% vs 33%, p < 0.05). With symptoms lasting >12 hours on arrival, troponin T performed better, with 100% sensitivity and a negative predictive value of 100% in the 6-hour retest. For exclusion of damage, the two tests have similar and reliable diagnostic capacities 12 hours after the onset of symptoms. The bedside diagnosis or exclusion of acute myocardial infarction was carried out rapidly (within 20 minutes) and reliably by the CCU nurses.

References

Sep 1, 1991·Journal of Internal Medicine·B W KarlsonA Hjalmarson
Jun 1, 1988·Annals of Internal Medicine·T H Lee, L Goldman
Oct 1, 1987·Medical Decision Making : an International Journal of the Society for Medical Decision Making·G A Diamond
Sep 1, 1994·The New England Journal of Medicine·P R PuleoJ L Zimmerman
Mar 1, 1993·Annals of Emergency Medicine·A KarczK Williams

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Citations

Aug 18, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·M P HudsonE M Ohman
Jul 4, 2001·Clinical Chemistry and Laboratory Medicine : CCLM·F PaganiM Panteghini
Mar 22, 2000·Clinical Chemistry and Laboratory Medicine : CCLM·M PanteghiniG Bonetti
Mar 27, 1999·Clinical Chemistry and Laboratory Medicine : CCLM·J P Chapelle
Sep 15, 2000·Clinical Chemistry and Laboratory Medicine : CCLM·M Müller-BardorffH A Katus
Oct 9, 2002·Clinica Chimica Acta; International Journal of Clinical Chemistry·Alexander KratzElizabeth Lee-Lewandrowski
Sep 5, 2013·International Journal of Cardiology·Madeleine H E Bruins SlotFrans H Rutten
Mar 14, 2007·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Kaat SiebensChristiaan Vrints
Aug 26, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J C StolearD Verbeelen
Aug 21, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Gerald N AudetLisa R Leon
Aug 7, 1999·International Journal of Clinical & Laboratory Research·K PenttiläI Penttilä
Sep 25, 2001·Thrombosis Research·C W Hamm

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