PMID: 2504342Jul 8, 1989Paper

Excess benign melanocytic naevi after chemotherapy for malignancy in childhood

BMJ : British Medical Journal
B HughesC C Bailey

Abstract

To see whether children who have had chemotherapy develop increased numbers of moles. Blind assessment of patients having chemotherapy and subsequent comparison with the first suitable patients matched for age and sex who were attending the clinic during the same period after having completed treatment. Controls were obtained the following year by taking the first suitable patients attending a routine dermatology outpatient clinic who matched the study groups for age and sex. Referrals to a paediatric oncology clinic and a dermatology clinic at two city hospitals. The group receiving chemotherapy comprised all 32 patients with acute lymphatic leukaemia, lymphoma, and rhabdomyosarcoma who were attending the paediatric oncology clinic on two mornings a week during October 1987 to March 1988. The group who had completed treatment comprised 32 patients who were attending for follow up during the same period and who matched the first group for age and sex. Thirty two other patients attending the dermatology outpatient clinic with unrelated skin conditions served as controls. Definite increase in numbers of moles on children after a course of chemotherapy. Moles were counted by one observer on defined areas of the body and divided in...Continue Reading

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