Excess mortality, causes of death and prognostic factors in anorexia nervosa

The British Journal of Psychiatry : the Journal of Mental Science
Fotios C PapadopoulosLisa Ekselius

Abstract

Anorexia nervosa is a mental disorder with high mortality. To estimate standardised mortality ratios (SMRs) and to investigate potential prognostic factors. Six thousand and nine women who had in-patient treatment for anorexia nervosa were followed-up retrospectively using Swedish registers. The overall SMR for anorexia nervosa was 6.2 (95% CI 5.5-7.0). Anorexia nervosa, psychoactive substance use and suicide had the highest SMR. The SMR was significantly increased for almost all natural and unnatural causes of death. The SMR 20 years or more after the first hospitalisation remained significantly high. Lower mortality was found during the last two decades. Younger age and longer hospital stay at first hospitalisation was associated with better outcome, and psychiatric and somatic comorbidity worsened the outcome. Anorexia nervosa is characterised by high lifetime mortality from both natural and unnatural causes. Assessment and treatment of psychiatric comorbidity, especially alcohol misuse, may be a pathway to better long-term outcome.

References

Jan 1, 1992·Acta Psychiatrica Scandinavica·J Joergensen
Jul 1, 1992·The British Journal of Psychiatry : the Journal of Mental Science·A H CrispL K Hsu
Mar 1, 1989·Acta Psychiatrica Scandinavica·N ZilberY Lerner
Nov 1, 1988·Psychological Medicine·G C Patton
Nov 1, 1965·The Journal of Clinical Endocrinology and Metabolism·H F Klinefelter
Jan 1, 1995·Psychological Medicine·E D EckertR Crosby
Oct 1, 1994·Acta Psychiatrica Scandinavica·A K Pagsberg, A R Wang
Jun 1, 1993·Acta Psychiatrica Scandinavica·C E Norring, S S Sohlberg
Dec 1, 1996·Acta Psychiatrica Scandinavica·S Møller-MadsenS Nielsen
Mar 1, 1997·The British Journal of Psychiatry : the Journal of Mental Science·E C Harris, B Barraclough
Jun 1, 1997·Acta Psychiatrica Scandinavica·A Favaro, P Santonastaso
Jul 11, 1998·The American Journal of Psychiatry·P F SullivanA Pickering
Dec 16, 1998·The British Journal of Psychiatry : the Journal of Mental Science·E C Harris, B Barraclough
Apr 7, 1999·The International Journal of Eating Disorders·C Emborg
Jun 1, 1999·The International Journal of Eating Disorders·S CrowP Thuras
May 9, 2000·The International Journal of Eating Disorders·D B HerzogM B Keller
Sep 9, 2000·Schizophrenia Research·U OsbyP Sparén
Mar 15, 2001·Cancer Causes & Control : CCC·L MellemkjaerJ H Olsen
Jul 19, 2001·Psychological Medicine·B LöweW Herzog
Sep 26, 2001·Archives of General Psychiatry·U OsbyP Sparén
Dec 4, 2001·The British Journal of Psychiatry : the Journal of Mental Science·M JoukamaaV Lehtinen
Jan 30, 2002·Diabetes Care·Søren NielsenAnne-Grethe Mølbak
Aug 3, 2002·The American Journal of Psychiatry·Hans-Christoph Steinhausen
Feb 13, 2003·Archives of General Psychiatry·Pamela K KeelDavid B Herzog
Mar 13, 2003·Mayo Clinic Proceedings·Sergio R KorndörferL Joseph Melton
May 3, 2003·The American Journal of Psychiatry·Sing LeeL K George Hsu
Mar 11, 2004·JAMA : the Journal of the American Medical Association·Karin B Michels, Anders Ekbom
Apr 1, 2005·The American Journal of Psychiatry·Harry R MillarJohn M Eagles
Apr 12, 2005·The International Journal of Eating Disorders·Rhonda F BrownC Laird Birmingham
Aug 4, 2005·Journal of Endocrinological Investigation·E MannucciC M Rotella
Sep 1, 2005·The International Journal of Eating Disorders·C Laird BirminghamMin Gao
Oct 19, 2005·The International Journal of Eating Disorders·Manfred M FichterSusanne Hedlund
Aug 23, 2006·Cardiology in Review·Deena Casiero, William H Frishman
Oct 24, 2006·Eating Behaviors·Doris AnzengruberCynthia M Bulik

❮ Previous
Next ❯

Citations

Jun 12, 2013·Behaviour Research and Therapy·Amy Manuel, Tracey D Wade
Mar 24, 2011·Psychological Medicine·E AttiaY Wang
Mar 24, 2012·Psychological Medicine·J M EaglesS Bhattacharya
Nov 17, 2010·Molecular Psychiatry·K WangUNKNOWN Price Foundation Collaborative Group
Apr 27, 2010·Eating Disorders·Mark L NorrisNicole Obeid
Sep 2, 2009·Annual Review of Medicine·Evelyn Attia
Jan 1, 2013·Journal of Eating Disorders·Lois J Surgenor, Sarah Maguire
Aug 1, 2012·PloS One·Olaia CarreraMartien J H Kas
Sep 12, 2013·Bulletin of the Menninger Clinic·Rebecca A Wagner, Chelsea R MacCaughelty
Feb 23, 2011·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Sigrid Bjørnelv
Oct 1, 2013·Eating and Weight Disorders : EWD·Giovanni ScanelliEmilia Manzato
Nov 8, 2013·Eating and Weight Disorders : EWD·Sonja KochManfred Fichter
Jul 12, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·David J BowdenDaniel J Scoffings
Jan 28, 2014·Progress in Neuro-psychopharmacology & Biological Psychiatry·Yuri NagaharaKenji Fukui
Mar 2, 2013·Eating and Weight Disorders : EWD·L PinganiS Ferrari
Sep 17, 2014·BioPsychoSocial Medicine·Keisuke KawaiNobuyuki Sudo
Sep 13, 2014·Comprehensive Psychiatry·Aparna KeshaviahKamryn T Eddy
Sep 10, 2010·Psychiatry Research·René Klinkby StøvingKirsten Hørder
May 30, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Gerald F M Russell, Anne Ward
Nov 2, 2013·BMC Psychiatry·Marloes S OudijnDamiaan Denys
Jun 14, 2013·Eating and Weight Disorders : EWD·Charlotte JaiteChristian J Bachmann
Apr 10, 2012·European Child & Adolescent Psychiatry·Elisabet WentzMaria Råstam
Feb 18, 2016·Eating and Weight Disorders : EWD·Margarita SalaElizabeth A Black
Oct 18, 2011·Expert Review of Obstetrics & Gynecology·Elizabeth R HoffmanCynthia M Bulik
Apr 30, 2013·The American Journal of Emergency Medicine·Stacy A TrentPhilip S Mehler
Mar 29, 2013·Journal of Psychiatric Research·Stephanie ZerwasCynthia M Bulik
Jan 16, 2016·The International Journal of Eating Disorders·Manfred Maximilian Fichter, Norbert Quadflieg
Oct 26, 2012·L'Encéphale·H RouxN Godart
Mar 16, 2011·European Journal of Internal Medicine·Riccardo Dalle Grave
Aug 9, 2015·Eating and Weight Disorders : EWD·Luca ErrichielloIgnazio Senatore
Jun 23, 2010·Physiology & Behavior·Kimberly P Kinzig, Sara L Hargrave
May 5, 2010·Physiology & Behavior·D A KleinB T Walsh
Nov 10, 2009·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·C GelegenM J H Kas
Jul 15, 2015·The American Journal of Medicine·Patricia WestmorelandPhilip S Mehler
May 12, 2009·Journal of Psychiatric Research·Antonio PretiUNKNOWN ESEMeD-WMH Investigators

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Related Papers

The American Journal of Psychiatry
Hans-Christoph Steinhausen
Lancet
Janet TreasureNancy Zucker
The International Journal of Eating Disorders
Nancy D BerkmanCynthia M Bulik
© 2021 Meta ULC. All rights reserved