Excess of adiposity in female children and adolescents with juvenile idiopathic arthritis.

Clinical Rheumatology
Michelle Cavalcante CaetanoMaria Odete Esteves Hilário

Abstract

This study aims to evaluate the body composition (BC) of female children and adolescents with juvenile idiopathic arthritis (JIA). A cross-sectional, controlled study was performed to compare the BC between 42 JIA girls and 35 healthy controls, matched for age and gender. Weight and height were used to calculate body mass index (BMI), classified as a Z-score (Z-BMI). BC was evaluated by dual-energy X-ray absorptiometry (DXA; DPX-L, Lunar). The fat mass index (FMI) was calculated as the ratio between total fat mass and height squared (kilograms per square metre). The lean mass index (LMI) was calculated as the ratio between total lean mass and height squared (kilograms per square metre). In JIA patients, the median of age was 13 years (6-19) and median disease duration was 84 months (10.0-215.0). The main disease subtype was polyarticular arthritis (54.8%). We observed that 61.9% of patients had normal Z-BMI. JIA girls had higher median Z-BMI scores (0.17 vs. -0.48, p = 0.034), total body fat percentages (26.5% vs. 16.4%, p = 0.001), truncal fat (4.52 vs. 2.32, p = 0.011) and FMI (4.83 vs. 2.23, p < 0.001). For LMI, there was no difference between JIA girls and controls (13.45 vs. 12.45, p = 0.212). We did not find association b...Continue Reading

References

Apr 4, 2000·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·G M KiebzakZ Y Zhang
Jan 11, 2003·Arthritis and Rheumatism·Margaretha A HaugenØystein Førre
Oct 7, 2004·Rheumatology·A G ClearyJ E Davidson
Sep 7, 2005·Statistics in Medicine·E BorghiUNKNOWN WHO Multicentre Growth Reference Study Group
Mar 6, 2007·Lancet·Angelo Ravelli, Alberto Martini
Apr 25, 2007·Scandinavian Journal of Rheumatology·V LillebyO Førre
Sep 7, 2007·Archives of Disease in Childhood·Jonathan C K Wells, Mary S Fewtrell
Sep 30, 2008·Arthritis and Rheumatism·Otto T H M LelieveldEllen van Weert
Oct 31, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Maria H KniazewskaKarolina Sieroń-Stołtny
May 6, 2009·Pediatric Radiology·Maura Helba, Larry A Binkovitz
Jul 16, 2009·Rheumatology·Christina BookLennart T H Jacobsson
Nov 3, 2009·The Journal of Clinical Endocrinology and Metabolism·Susanne BechtoldHans Peter Schwarz
Jan 22, 2010·The American Journal of Clinical Nutrition·Jonathan C K WellsMary S Fewtrell

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Citations

Mar 19, 2013·Rheumatology·Elizabeth J CoulsonHelen E Foster
Mar 7, 2015·Scandinavian Journal of Rheumatology·S SchenckJ Klotsche
Sep 3, 2014·Scandinavian Journal of Rheumatology·M-M GrönlundK Laitinen
Dec 17, 2017·The Journal of Rheumatology·Aaida SamadUNKNOWN CARRA Legacy Registry Investigators
Jun 5, 2013·Arthritis Research & Therapy·Julie BarsalouEarl D Silverman

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