PMID: 8971883Dec 1, 1996Paper

Excess prevalence of non diabetic renal disease in native American children in Manitoba

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
B BullochMalcolm Ogborn

Abstract

We undertook a 1-year prospective point prevalence study to test the hypothesis that there is an excess of non-diabetic renal disease in native American children; 29.6% (73/247) of the population attending the only regional pediatric nephrology clinic in 1993 were native compared with 8.2% of the Manitoba population in this age group (odds ratio = 4.4, P < 0.001). Patients were classified as low risk (normal renal function, no deterioration expected), high risk (normal renal function, deterioration probable), or established chronic renal failure (creatinine clearance chronically low or post renal transplant). Patients were further classified as suffering from congenital renal anomalies, genetic or metabolic disease, or acquired renal disease. Odds ratios were calculated based on data from the Aboriginal Peoples' Population Survey and Statistics Canada census data. The odds ratios for low-risk renal disease, high-risk renal disease, and chronic renal failure were 3.8, 5.6, and 6.3, respectively (P < 0.001 in all categories). The odds ratios for congenital, genetic, or acquired disease were 4.5 (P < 0.001), 0.9 (P = ns), and 6.1 (P < 0.001), respectively. Native American children in Manitoba demonstrate increased prevalence of se...Continue Reading

Associated Clinical Trials

Citations

Jun 22, 2010·Transplantation·Leroy J StorsleyMartin Karpinski
Aug 29, 2012·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Susan M SamuelUNKNOWN Pediatric Renal Outcomes Canada Group
Feb 9, 2012·International Journal of Pediatrics·Allison B DartHeather J Dean
Dec 8, 2009·Pediatric Clinics of North America·Elizabeth A C SellersHeather J Dean
Mar 30, 2004·Diabetes Care·Zachary T Bloomgarden
Feb 21, 2009·Diabetes Care·Elizabeth A C SellersMalcolm Ogborn
Mar 10, 1998·Clinical Pediatrics·H Dean
Dec 6, 2007·Pediatric Diabetes·Heather J Dean, Elizabeth A C Sellers

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