Excess stroke incidence in young Aboriginal people in South Australia: Pooled results from two population-based studies

International Journal of Stroke : Official Journal of the International Stroke Society
Anna H BalabanskiTimothy J Kleinig

Abstract

Background Retrospective data indicate increased stroke incidence in Aboriginal/Torres Strait Islander (Indigenous) Australians, possibly with poorer outcomes. We present the first prospective population-based stroke incidence study in Indigenous Australians. Methods We pooled data from ASCEND and SEARCH, two prospective "ideal" South Australian stroke incidence studies, ASCEND conducted in urban Northwestern Adelaide (2009-2010) and SEARCH in five South Australian rural centers (2009-2011). We calculated age-standardized incidence for Aboriginal and non-Aboriginal people. Results The study population comprised 261,403 inhabitants. Among 432 first-ever strokes, 13 were in Aboriginal people (median age 51 vs. 78 years for non-Aboriginal people, p < 0.001). Age-standardized stroke incidence per 100,000 in Aboriginal patients (116, 95% CI: 95-137) was nearly two-fold that of non-Aboriginal patients (67, 95% CI: 51-84). Age-stratified excess incidence in Aboriginal people was restricted to those aged < 55 years (incidence rate ratio (IRR) 3.5, 95% CI: 2-7), particularly for intracerebral hemorrhage (IRR: 16, 95% CI: 4-61). Conclusion The excess stroke incidence in Aboriginal South Australians appears substantial, especially in thos...Continue Reading

References

Mar 1, 1996·Stroke; a Journal of Cerebral Circulation·C L Sudlow, C P Warlow
Apr 16, 2011·Stroke; a Journal of Cerebral Circulation·Judith M KatzenellenbogenJames P Codde
Mar 14, 2013·Stroke; a Journal of Cerebral Circulation·James M LeydenJennene Greenhill
Oct 4, 2016·International Journal of Stroke : Official Journal of the International Stroke Society·Jonathan NewburyCraig S Anderson
Jul 1, 2017·The Medical Journal of Australia·Michael G Marmot

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Citations

Feb 23, 2020·The Medical Journal of Australia·Nicole Lowres, Ben Freedman
Feb 6, 2020·Journal of Neurology, Neurosurgery, and Psychiatry·Esther BootAnil M Tuladhar
Aug 7, 2019·Internal Medicine Journal·David Blacker, Elizabeth Armstrong
Jul 11, 2019·Neural Regeneration Research·Nan-Xing YiTing Zhang
Oct 27, 2020·Stroke; a Journal of Cerebral Circulation·Bruce Ovbiagele
Oct 27, 2020·Stroke; a Journal of Cerebral Circulation·Amytis TowfighiBruce Ovbiagele

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