Exchange transfusion safety and outcomes in neonatal hyperbilirubinemia.

Journal of Perinatology : Official Journal of the California Perinatal Association
Mattie F WolfRachel G Greenberg

Abstract

To characterize the prevalence of exchange transfusion (ET), clinical characteristics of infants receiving ET, and ET-associated morbidity and mortality. We conducted a multicenter cohort study of infants ≥23 weeks of gestational age (GA) with hyperbilirubinemia who underwent ET within 30 days of birth from 1997 to 2016. We examined clinical characteristics and adverse events after ET. We used multivariable logistic regression to examine the association between clinical risk factors and death. A total of 1252 infants were included; 4% died within 7 days of ET and 6% died before discharge. Compared with infants ≥37 weeks of GA, infants ≤29 weeks of GA had greater odds of death (adjusted odds ratio [95% confidence interval] = 20.08 [7.32, 55.07]). Infants ≤ 29 weeks of GA had greater odds of death following ET compared with term infants. These data will support clinicians in evaluating risks and prognosis for infants who require ET.

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Citations

Jul 24, 2020·Current Diabetes Reports·Sydney PetersSarbattama Sen
May 14, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Mattie F WolfRachel G Greenberg
Nov 24, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ling DuanHongbing Hu
Aug 7, 2021·Clinics in Perinatology·Cathy Hammerman, Michael Kaplan
Aug 6, 2021·European Journal of Pediatrics·Sitarah MathiasSuman Rao
Sep 3, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ramesh Vidavalur, Srisatish Devapatla
Oct 13, 2021·Journal of Perinatology : Official Journal of the California Perinatal Association·Warren N RosenfeldUNKNOWN Jasmine Study Group

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Methods Mentioned

BETA
SGA

Software Mentioned

STATA
Pediatrix

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