Exchangeability of Qsr1p, a large ribosomal subunit protein required for subunit joining, suggests a novel translational regulatory mechanism

FEBS Letters
F A DickB L Trumpower

Abstract

Qsr1p is a 60S ribosomal subunit protein that is necessary for joining of large and small ribosomal subunits and is also one of the last proteins assembled onto the 60S ribosomal subunit in the cytoplasm. The finding that Qsr1p is identical to L7, a protein previously shown to cycle on and off large ribosomal subunits in the cytoplasm, suggests that the addition of Qsr1p onto the 60S ribosomal subunit could be utilized as a translational regulatory mechanism by limiting the supply of functional 60S subunits.

References

Jan 1, 1978·Methods in Cell Biology·J R Warner, C Gorenstein
Feb 16, 1978·Biochimica Et Biophysica Acta·T KruiswijkJ M Krop
Jan 11, 1991·Advances in Genetics·J L Woolford
Jan 1, 1991·Methods in Enzymology·H A RauéR J Planta
Oct 23, 1990·Biochimica Et Biophysica Acta·F CamposS Zinker
Mar 28, 1972·Journal of Molecular Biology·J R Warner, S A Udem
May 1, 1994·Human Molecular Genetics·A A FarmerE J Stanbridge
Aug 1, 1993·The Plant Journal : for Cell and Molecular Biology·I MartyY Meyer
Nov 15, 1993·Biochemical and Biophysical Research Communications·D P EisingerG Serrero
Jan 1, 1996·Progress in Nucleic Acid Research and Molecular Biology·J P Ballesta, M Remacha
Dec 15, 1996·Experimental Cell Research·D Tollervey
Sep 1, 1997·Molecular and Cellular Biology·D P EisingerB L Trumpower

❮ Previous
Next ❯

Citations

Nov 17, 2007·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Mitsuhiro NishimuraYuji Kobayashi
Apr 16, 2005·Molecular and Cellular Biology·Matthew WestArlen W Johnson
May 19, 2007·FEBS Letters·Ivo Zemp, Ulrike Kutay
Aug 13, 2008·The Plant Journal : for Cell and Molecular Biology·Akihiro ImaiTaku Takahashi
Nov 24, 1999·Molecular and Cellular Biology·D KresslerJ de La Cruz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.